P5022
Pamoic acid disodium salt
Synonym(s):
4,4′-Methylenebis(3-hydroxy-2-naphthoic acid), Embonic acid, Sodium pamoate
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About This Item
Linear Formula:
C23H14O6Na2
CAS Number:
Molecular Weight:
432.33
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352106
EC Number:
229-653-1
MDL number:
Form:
powder
form
powder
Quality Level
SMILES string
[Na].OC(=O)c1cc2ccccc2c(Cc3c(O)c(cc4ccccc34)C(O)=O)c1O
InChI
1S/C23H16O6.Na.H/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;;/h1-10,24-25H,11H2,(H,26,27)(H,28,29);;
InChI key
ZRZSXMUASGHHKP-UHFFFAOYSA-N
Related Categories
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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The combination of metabolic modulators with chemotherapy holds vast promise for effective inhibition of tumor progression and invasion. Herein, a ratiometric codelivery platform is developed for metformin (MET), a known metabolic modulator and topotecan (TPT), a chemotherapeutic drug, by engineering
O Gavrilova-Ruch et al.
The Journal of membrane biology, 188(2), 137-149 (2002-08-13)
Human IGR1 cells are a model for malignant melanoma. Since progression through the cell cycle is accompanied by transient cell hyperpolarization, we studied the properties of potassium and chloride ion channels and their impact on cell growth. The major potassium
S Handali et al.
The Southeast Asian journal of tropical medicine and public health, 28 Suppl 1, 22-25 (1997-01-01)
A community survey was conducted in Gran Dani Valley, Jayawijaya District, Irian Jaya Province, Indonesia. A total of 537 adults were asked whether they experienced epilepsy, and were physically examined for cysticercosis cysts. Forty-eight percent experienced at least one attack
Richard R Neubig
Molecular pharmacology, 78(4), 558-559 (2010-07-24)
Many pharmacological agents include "inactive" constituents that are used to alter the solubility, stability, or pharmaceutical properties of a drug. These "salts" are often ignored, and the "active ingredient" gets all of the attention. Pamoic acid (4-[(3-carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylic acid) has been
Corinne Hazan et al.
BMC structural biology, 8, 22-22 (2008-04-18)
DNA polymerase beta (pol beta), the error-prone DNA polymerase of single-stranded DNA break repair as well as base excision repair pathways, is overexpressed in several tumors and takes part in chemotherapeutic agent resistance, like that of cisplatin, through translesion synthesis.
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