S0327
Scutellarein
≥98% (HPLC)
Synonym(s):
4′,5,6,7-Tetrahydroxyflavone, 6-Hydroxyapigenin
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About This Item
Empirical Formula (Hill Notation):
C15H10O6
CAS Number:
Molecular Weight:
286.24
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
biological source
Erigeron breviscapus
Quality Level
assay
≥98% (HPLC)
form
powder
storage condition
protect from light
color
yellow
solubility
DMSO: 1 mg/mL, clear, greenish-yellow
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
2-8°C
SMILES string
Oc1ccc(cc1)C2=CC(=O)c3c(O)c(O)c(O)cc3O2
InChI
1S/C15H10O6/c16-8-3-1-7(2-4-8)11-5-9(17)13-12(21-11)6-10(18)14(19)15(13)20/h1-6,16,18-20H
InChI key
JVXZRQGOGOXCEC-UHFFFAOYSA-N
Biochem/physiol Actions
Flavonoid that is selectively cytotoxic toward cancer cells. Induces mitochondrial ROS, DNA damage, and metabolic suppression, preferentially in tumor cells. Scutellarein has been shown to have better absorption than scutellarin in Caco-2 monolayer cells.
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Mi-Sun Yu et al.
Bioorganic & medicinal chemistry letters, 22(12), 4049-4054 (2012-05-15)
Severe acute respiratory syndrome (SARS) is an infectious disease with a strong potential for transmission upon close personal contact and is caused by the SARS-coronavirus (CoV). However, there are no natural or synthetic compounds currently available that can inhibit SARS-CoV.
Xuesong Liu et al.
Journal of pharmaceutical sciences, 100(6), 2452-2459 (2011-01-20)
Antisolvent crystallization can be used as an alternative to cooling or evaporation for the separation and purification of solid product in the pharmaceutical industry. To improve the process understanding of antisolvent crystallization, the use of in-line tools is vital. In
Jian-feng Xing et al.
Acta pharmacologica Sinica, 32(5), 655-663 (2011-04-26)
To study the metabolic and pharmacokinetic profile of scutellarin, an active component from the medical plant Erigeron breviscapus (Vant) Hand-Mazz, and to investigate the mechanisms underlying the low bioavailability of scutellarin though oral or intravenous administration in rats. HPLC method