SML0679
Danshensu sodium salt
≥98% (HPLC)
Synonym(s):
(R)-α,3,4-Trihydroxy-benzenepropanoic acid sodium salt, (R)-(+)-3-(3,4-Dihydroxyphenyl)lactic acid, 3-(3′,4′-Dihydroxyphenyl)-(2R)-lactic acid sodium salt, DS 182, Dan Shen Su, Dan shen suan A, Salianic acid A, Salvianic acid A
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About This Item
Empirical Formula (Hill Notation):
C9H9O5 · Na
CAS Number:
Molecular Weight:
220.15
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Quality Level
assay
≥98% (HPLC)
form
powder
optical activity
[α]/D +30 to +40°, c = 1 in H2O
color
white to beige
solubility
H2O: 20 mg/mL, clear
storage temp.
2-8°C
SMILES string
OC1=C(O)C=CC(C[C@@H](O)C([O-])=O)=C1.[Na+]
InChI
1S/C9H10O5.Na/c10-6-2-1-5(3-7(6)11)4-8(12)9(13)14;/h1-3,8,10-12H,4H2,(H,13,14);/q;+1/p-1/t8-;/m1./s1
InChI key
ZMMKVDBZTXUHFO-DDWIOCJRSA-M
Biochem/physiol Actions
Danshensu is an active component of Salvia miltiorrhiza (Danshen) that suppresses the formation of reactive oxygen species, inhibits platelet adhesion and aggregation, and protects myocardium against ischemia. Danshensu is cardioprotective, which protects myocardium from the reperfusion injury and inhibits apoptosis of H9c2 cardiomyocytes via Akt and ERK1/2 phosphorylation.
Danshensu is cardioprotective, which protects myocardium from the reperfusion injury and inhibits apoptosis of H9c2 cardiomyocytes via Akt and ERK1/2 phosphorylation.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Zihua Wang et al.
Analytica chimica acta, 1140, 145-152 (2020-11-22)
Interleukin-6 (IL-6) is of high importance for disease diagnosis and prognosis in human health since it's a crucial component in immune homeostasis, hematopoiesis, and metabolism. Herein, an immunosensor has been developed for monitoring IL-6, which is fabricated by Au nanoparticles
Ye Jin et al.
Journal of pharmaceutical and biomedical analysis, 77, 32-39 (2013-01-30)
The application of near infrared (NIR) spectroscopy for on-line quantitative monitoring of alcohol precipitation of the Danhong injection was investigated. For the NIR measurements, two fiber optic probes designed to transmit NIR radiation through a 2mm path length flow cell
Jian-ping Zhang et al.
Planta medica, 79(9), 744-752 (2013-05-24)
The traditional Chinese medicinal herb Danshen (Salvia miltiorrhiza), first recorded in the "Shen Nong's Herbal Classic", has long been used to treat cardiovascular conditions, although the mechanism(s) underlying its effects remain unclear. Here, an iron dextran injection (50 mg ·