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Merck

150215

9(10H)-Acridanone

99%

Synonym(s):

Acridone, 9,10-Dihydro-9-oxoacridine

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About This Item

Empirical Formula (Hill Notation):
C13H9NO
CAS Number:
Molecular Weight:
195.22
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
209-434-7
Beilstein/REAXYS Number:
7104
MDL number:
Assay:
99%
Form:
solid
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Product Name

9(10H)-Acridanone, 99%

InChI key

FZEYVTFCMJSGMP-UHFFFAOYSA-N

InChI

1S/C13H9NO/c15-13-9-5-1-3-7-11(9)14-12-8-4-2-6-10(12)13/h1-8H,(H,14,15)

SMILES string

O=C1c2ccccc2Nc3ccccc13

assay

99%

form

solid

mp

>300 °C (lit.)

λmax

380 nm
399 nm (2nd)

Quality Level

Gene Information

human ... ABCB1(5243)

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Application

9(10H)-Acridanone (acridone) was used in the preparation of methyl 9,10-dihydro-9-oxoacridine-10-pentanoate.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Dadi Chen et al.
Biotechnology for biofuels, 13, 130-130 (2020-07-24)
Considerable interest has been expressed in the development of anaerobic digestion (AD) of straw to solve the environmental problems caused by the dumping and burning of straw and to generate clean energy. However, the poor biodegradability of straw and the
A novel acridone derivative for the fluorescence tagging and mass spectrometric sequencing of peptides.
Chemical Communications (Cambridge, England), 16, 1529-1530 (1997)
Emerson F Marques et al.
European journal of medicinal chemistry, 54, 10-21 (2012-05-18)
Cathepsins, also known as lysosomal cysteine peptidases, are members of the papain-like peptidase family, involved in different physiological processes. In addition, cathepsins are implicated in many pathological conditions. This report describes the synthesis and evaluation of a series of N-arylanthranilic
Giuseppe Manfroni et al.
Journal of medicinal chemistry, 52(10), 3354-3365 (2009-04-25)
We report the synthesis and structure-activity relationship (SAR) of a large series of acridones and acridone-fragment derivatives designed on the basis of the selective antihepatitis C virus (HCV) activity shown by acridone 2, previously studied as a potential antibovine viral
Florian Astelbauer et al.
Vector borne and zoonotic diseases (Larchmont, N.Y.), 11(7), 793-798 (2011-03-23)
Visceral and cutaneous leishmaniases are an important public health problem in endemic geographic regions in 88 countries worldwide, with around 12 million infected people. Treatment options are limited due to toxicity and teratogenicity of the available drugs, response problems in

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