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Merck

P60205

2-Pyridinealdoxime methiodide

99%

Synonym(s):

2-PAM, 2-PAM iodide, Pralidoxime iodide

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About This Item

Empirical Formula (Hill Notation):
C7H11IN2O
CAS Number:
94-63-3
Molecular Weight:
266.08
NACRES:
NA.22
PubChem Substance ID:
24898726
UNSPSC Code:
12352100
EC Number:
202-349-6
MDL number:
MFCD00011982
Assay:
99%
Form:
solid

Key Documents

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InChI

1S/C7H8N2O.HI/c1-9-5-3-2-4-7(9)6-8-10;/h2-6H,1H3;1H

InChI key

QNBVYCDYFJUNLO-UHFFFAOYSA-N

SMILES string

[I-].C[n+]1ccccc1\C=N\O

assay

99%

form

solid

mp

220 °C (dec.) (lit.)

storage temp.

2-8°C

Quality Level

200

Gene Information

human ... ACHE(43)

Related Categories

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
08020HG
07220JV
06005MW
10110DQ
04511TI

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Kimberly D Spradling et al.
Journal of neuroinflammation, 8, 83-83 (2011-07-23)
Organophosphorus nerve agents irreversibly inhibit acetylcholinesterase, causing a toxic buildup of acetylcholine at muscarinic and nicotinic receptors. Current medical countermeasures to nerve agent intoxication increase survival if administered within a short period of time following exposure but may not fully
Pavel Škaloud et al.
Journal of phycology, 56(3), 574-591 (2020-02-18)
We performed a comparison of molecular and morphological diversity in a freshwater colonial genus Synura (Chrysophyceae, Stramenopiles), using the island of Newfoundland (Canada) as a case study. We examined the morphological species diversity in collections from 79 localities, and compared
Kazuhito Nomura et al.
Scientific reports, 10(1), 15834-15834 (2020-09-29)
Whether central apnoea or hypopnoea can be induced by organophosphorus poisoning remains unknown to date. By using the acute brainstem slice method and multi-electrode array system, we established a paraoxon (a typical acetylcholinesterase inhibitor) poisoning model to investigate the time-dependent
Eduardo A González et al.
Archives of toxicology, 94(6), 2149-2162 (2020-04-19)
Organophosphate (OP) threat agents can trigger seizures that progress to status epilepticus, resulting in persistent neuropathology and cognitive deficits in humans and preclinical models. However, it remains unclear whether patients who do not show overt seizure behavior develop neurological consequences.
Qiqi Zheng et al.
Analytica chimica acta, 982, 78-83 (2017-07-25)
An electrochemical method based on non-enzymatic inhibition for the determination of organophosphorus pesticide (OPPs) using pralidoxime chloride (PAM-Cl) as a universal electrochemical probe was reported. Cyclic voltammetry was performed to characterize the redox properties of pralidoxime and OPPs. Differential pulse
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