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8.52020

Fmoc-Tyr(tBu)-OH

Novabiochem®

Synonym(s):

Fmoc-Tyr(tBu)-OH, N-α-Fmoc-O-t.-butyl-L-tyrosine

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About This Item

Empirical Formula (Hill Notation):
C28H29NO5
CAS Number:
71989-38-3
Molecular Weight:
459.53
UNSPSC Code:
12352209
EC Index Number:
276-262-7
NACRES:
NA.22
MDL number:
MFCD00037129
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Quality Level

400

product line

Novabiochem®

form

solid

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

mp

143-155 °C

application(s)

peptide synthesis

functional group

hydroxyl

storage temp.

2-30°C

SMILES string

N(C(Cc4ccc(cc4)OC(C)(C)C)C(=O)O)C(=O)OCC1c2c(cccc2)c3c1cccc3

InChI

1S/C28H29NO5/c1-28(2,3)34-19-14-12-18(13-15-19)16-25(26(30)31)29-27(32)33-17-24-22-10-6-4-8-20(22)21-9-5-7-11-23(21)24/h4-15,24-25H,16-17H2,1-3H3,(H,29,32)(H,30,31)

InChI key

JAUKCFULLJFBFN-UHFFFAOYSA-N

General description

High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities.
Standard building block for introduction of tyrosine amino-acid residues by Fmoc SPPS

Associated Protocols and Technical Articles
Fmoc-amino acids for Peptide Production
Cleavage and Deprotection Protocols for Fmoc SPPS

Application

Fmoc-Tyr(tBu)-OH Novabiochem®. CAS 71989-38-3, molar mass 459.55 g/mol.

Analysis Note

Color (visual): white to off white
Appearance of substance (visual): powder
Color index (0,5 M in DMF): ≤ 150 Hazen
Identity (IR): passes test
Enantiomeric purity: ≥ 99.8 % (a/a)
Purity (HPLC): ≥ 99.0 % (a/a)
Fmoc-ß-Ala-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-ß-Ala-Tyr(tBu) -OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-Tyr(tBu)-Tyr(tBu)-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-Tyr-OH (HPLC): ≤ 0.1 % (a/a)
Assay free amino acid (GC): ≤ 0.2 %
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Solubility (25 mmole in 50 ml DMF): clearly soluble
Assay (acidimetric): ≥ 98.0 %
Water (K. F.): ≤ 2.0 %
Ethyl acetate (HS-GC): ≤ 0.5 %
Acetate (IC): ≤ 0.02 %

To see the solvent systems used for TLC of Novabiochem® products please click here.

Other Notes

Replaces: 04-12-1037

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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