C7578
Coprostan-3-ol
≥98%
Synonym(s):
5β-Cholestan-3β-ol
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About This Item
Empirical Formula (Hill Notation):
C27H48O
CAS Number:
Molecular Weight:
388.67
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352001
EC Number:
206-638-8
MDL number:
Product Name
Coprostan-3-ol, ≥98%
InChI key
QYIXCDOBOSTCEI-NWKZBHTNSA-N
InChI
1S/C27H48O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h18-25,28H,6-17H2,1-5H3/t19-,20-,21+,22+,23-,24+,25+,26+,27-/m1/s1
SMILES string
[H]C12CCC3C4CCC([C@@H](C)CCCC(C)C)C4(C)CCC3C1(C)CCC(O)C2
assay
≥98%
form
powder
Quality Level
Related Categories
Application
Coprostan-3-ol can be used as an internal standard:
- For the determination of total amounts of cholesterol and 7-dehydrocholesterol reductase by GC-MS.
- For GC-MS estimation of EpHβA (16-hydroxy-β-amyrin) content of leaves expressing SAD1 and CYP51H10 genes with a green fluorescent protein.
It has been used as an internal standard for the determination of total amounts of cholesterol and 7-dehydrocholesterol reductase by GC/MS.
General description
Coprostan-3-ol is a cholesterol derivative that can be prepared from 5β-cholestan-3-one via reduction.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Matthew P Dale et al.
PloS one, 15(5), e0231980-e0231980 (2020-05-02)
Triterpenoids are high-value plant metabolites with numerous applications in medicine, agriculture, food, and home and personal care products. However, plants produce triterpenoids in low abundance, and their complex structures make their chemical synthesis prohibitively expensive and often impossible. As such
Characterization of placental cholesterol transport: ABCA1 is a potential target for in utero therapy of Smith-Lemli-Opitz syndrome.
Lindegaard ML, et al.
Human Molecular Genetics, 17(23), 3806-3813 (2008)
James Reed et al.
Metabolic engineering, 42, 185-193 (2017-07-09)
Plants are an excellent source of drug leads. However availability is limited by access to source species, low abundance and recalcitrance to chemical synthesis. Although plant genomics is yielding a wealth of genes for natural product biosynthesis, the translation of
A L Watne et al.
Annals of surgery, 197(5), 550-554 (1983-05-01)
Ileoproctostomy was performed in 32 patients (13 Female and 19 male), with polyposis coli ranging in age from 10 to 54 years. Seven patients (22%) developed cancer of the retained rectum with a median follow-up of 14 years. Two (20%)
The reduction of 5a-cholestan-3-one and 5?-cholestan-3-one by some boranes and hydroborates.
Contreras R and Mendoza L.
Steroids, 34(2), 121-124 (1979)
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