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Merck

12-1210

Glycine

SAJ special grade, ≥99.0%

Synonym(s):

Aminoacetic acid, Aminoethanoic acid, Glycocoll

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About This Item

Linear Formula:
NH2CH2COOH
CAS Number:
Molecular Weight:
75.07
EC Number:
200-272-2
UNSPSC Code:
12352116
PubChem Substance ID:
Beilstein/REAXYS Number:
635782
MDL number:
Assay:
≥99.0%
Grade:
SAJ special grade
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grade

SAJ special grade

assay

≥99.0%

form

crystalline powder

availability

available only in Japan

dilution

(for analytical testing)

pH

5.9-6.4 (50 g/L)

pKa (25 °C)

(1) 2.35, (2) 9.60, 2.35

mp

240 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

NCC(O)=O

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChI key

DHMQDGOQFOQNFH-UHFFFAOYSA-N

Biochem/physiol Actions

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.


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Storage Class

13 - Non Combustible Solids

wgk

WGK 1

ppe

Eyeshields, Gloves, type N95 (US)

flash_point_f

No data available

flash_point_c

No data available



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Alexander Carvajal-González et al.
Brain : a journal of neurology, 137(Pt 8), 2178-2192 (2014-06-22)
The clinical associations of glycine receptor antibodies have not yet been described fully. We identified prospectively 52 antibody-positive patients and collated their clinical features, investigations and immunotherapy responses. Serum glycine receptor antibody endpoint titres ranged from 1:20 to 1:60 000.
Richard A Felix et al.
Brain structure & function, 220(5), 2639-2652 (2014-06-30)
The mammalian superior paraolivary nucleus (SPON) is a major source of GABAergic inhibition to neurons in the inferior colliculus (IC), a well-studied midbrain nucleus that is the site of convergence and integration for the majority ascending auditory pathways en route
Zoé Husson et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(28), 9418-9431 (2014-07-11)
The principal neurons of the cerebellar nuclei (CN), the sole output of the olivo-cerebellar system, receive a massive inhibitory input from Purkinje cells (PCs) of the cerebellar cortex. Morphological evidence suggests that CN principal cells are also contacted by inhibitory