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Merck

104043

N-Phenyl-1-naphthylamine

reagent grade, 98%

Synonym(s):

1-(N-phenylamino)naphthalene, N-(1-Naphthyl)aniline, NPN

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About This Item

Linear Formula:
C10H7NHC6H5
CAS Number:
90-30-2
Molecular Weight:
219.28
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
57646802
EC Number:
201-983-0
Beilstein/REAXYS Number:
2211174
MDL number:
MFCD00003878
Assay:
98%
Form:
solid

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InChI key

XQVWYOYUZDUNRW-UHFFFAOYSA-N

InChI

1S/C16H13N/c1-2-9-14(10-3-1)17-16-12-6-8-13-7-4-5-11-15(13)16/h1-12,17H

SMILES string

N(c1ccccc1)c2cccc3ccccc23

grade

reagent grade

assay

98%

form

solid

bp

226 °C/15 mmHg (lit.)

mp

60-62 °C (lit.)

λmax

252 nm

Quality Level

100

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Application

N-Phenyl-1-naphthylamine can be used as fluorescent probe for the determination of critical micelle concentration of surfactants. N-Phenyl-1-naphthylamine was used in a method for determination of the concentration of organolithium and organomagnesium reagents. N-Phenyl-1-naphthylamine was used as hydrophobic probe to study the phase transitions of membrane lipids in whole cells .

Biochem/physiol Actions

N-Phenyl-1-naphthylamine turns fluorescent after binding to hydrophobic regions of cell membranes.

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Sens. 1B - STOT RE 2

target_organs

Blood

Storage Class

11 - Combustible Solids

wgk

WGK 2

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCX9482
MKCX9468
MKCX9480
0000237396
MKCV0353

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Daniel Pletzer et al.
PLoS pathogens, 14(6), e1007084-e1007084 (2018-06-22)
With the antibiotic development pipeline running dry, many fear that we might soon run out of treatment options. High-density infections are particularly difficult to treat due to their adaptive multidrug-resistance and currently there are no therapies that adequately address this
Xiaoyan Ning et al.
International journal of molecular sciences, 19(2) (2018-02-01)
Glucose oxidase (GOD, EC.1.1.3.4) specifically catalyzes the reaction of β-d-glucose to gluconic acid and hydrogen peroxide in the presence of oxygen, which has become widely used in the food industry, gluconic acid production and the feed industry. However, the poor
Peter Richter et al.
Antibiotics (Basel, Switzerland), 8(4) (2019-09-25)
Colistin (polymyxin E) is a membrane-destabilizing antibiotic used against Gram-negative bacteria. We have recently reported that the outer membrane prevents the uptake of antibacterial chlorophyllin into Gram-negative cells. In this study, we used sub-toxic concentrations of colistin to weaken this
Hanna-Leena Alakomi et al.
Journal of agricultural and food chemistry, 55(10), 3905-3912 (2007-04-19)
Gram-negative bacteria are important food spoilage and pathogenic bacteria. Their unique outer membrane (OM) provides them with a hydrophilic surface structure, which makes them inherently resistant to many antimicrobial agents, thus hindering their control. However, with permeabilizers, compounds that disintegrate
Guillaume Sautrey et al.
Antimicrobial agents and chemotherapy, 58(8), 4420-4430 (2014-05-29)
The development of novel antimicrobial agents is urgently required to curb the widespread emergence of multidrug-resistant bacteria like colistin-resistant Pseudomonas aeruginosa. We previously synthesized a series of amphiphilic neamine derivatives active against bacterial membranes, among which 3',6-di-O-[(2"-naphthyl)propyl]neamine (3',6-di2NP), 3',6-di-O-[(2"-naphthyl)butyl]neamine (3',6-di2NB)
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