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Merck

A6926

3-Amino-9-ethylcarbazole

chromogenic, tablet

Synonym(s):

9-Ethylcarbazol-3-amine, AEC

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About This Item

Empirical Formula (Hill Notation):
C14H14N2
CAS Number:
132-32-1
Molecular Weight:
210.27
NACRES:
NA.83
PubChem Substance ID:
24891156
UNSPSC Code:
12352204
EC Number:
205-057-7
MDL number:
MFCD00004964
Beilstein/REAXYS Number:
174969

Key Documents

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Product Name

3-Amino-9-ethylcarbazole, tablet

InChI key

OXEUETBFKVCRNP-UHFFFAOYSA-N

InChI

1S/C14H14N2/c1-2-16-13-6-4-3-5-11(13)12-9-10(15)7-8-14(12)16/h3-9H,2,15H2,1H3

SMILES string

CCn1c2ccccc2c3cc(N)ccc13

form

tablet

solubility

DMF: 1 tablet/5 mL

Quality Level

200

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Application

3-Amino-9-ethylcarbazole (AEC) has been used as a chromogen in immunohistochemistry to visualize the cells. It has also been used as a substrate in enzyme-linked immune absorbent spot (ELISpot).

Biochem/physiol Actions

3-Amino-9-ethylcarbazole is a peroxidase substrate suitable for use in immunoblotting and immunohistochemical staining procedures. This substrate produces an insoluble end product that is red in color and can be observed visually.

General description

3-Amino-9-ethylcarbazole is a chromogen

Preparation Note

Contains 20 mg substrate per tablet.

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

hcodes

H301,H350

Hazard Classifications

Acute Tox. 3 Oral - Carc. 1B

wgk

WGK 3

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
0000497112
0000497112
0000481729
0000468879
0000468882

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Respirology (Carlton, Vic.), 20(8), 1206-1212 (2015-08-21)
Exacerbations of allergic asthma are often triggered by respiratory viral infections. We have previously shown that in a T-helper type 2 (Th2)-biased cytokine environment, mouse and human airway epithelial cells (AEC) exhibit increased expression of pro-inflammatory and anti-viral genes in
Nicolas Kluger et al.
Clinical immunology (Orlando, Fla.), 158(2), 212-220 (2015-03-26)
Gastrointestinal dysfunction is a disabling manifestation of APECED possibly related to an autoimmune intestinal aggression. We evaluated its features in a cohort of 31 Finnish patients. The most frequent manifestations were constipation (48%), diarrhea, dysphagia and retrosternal pain (45%). AADC
Iresha N Ambepitiya Wickramasinghe et al.
PloS one, 10(6), e0128893-e0128893 (2015-06-04)
The initial interaction between viral attachment proteins and the host cell is a critical determinant for the susceptibility of a host for a particular virus. To increase our understanding of avian pathogens and the susceptibility of poultry species, we developed
Benoit Beuselinck et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 21(6), 1329-1339 (2015-01-15)
Selecting patients with metastatic clear-cell renal cell carcinoma (m-ccRCC) who might benefit from treatment with targeted tyrosine kinase inhibitors (TKI) is a challenge. Our aim was to identify molecular markers associated with outcome in patients with m-ccRCC treated with sunitinib.
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