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Merck

102741

2-Fluorobiphenyl

96%

Synonym(s):

1-Fluoro-2-phenylbenzene, o-Fluorodiphenyl

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About This Item

Linear Formula:
C6H5C6H4F
CAS Number:
Molecular Weight:
172.20
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
206-290-7
Beilstein/REAXYS Number:
2043175
MDL number:
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Product Name

2-Fluorobiphenyl, 96%

InChI key

KLECYOQFQXJYBC-UHFFFAOYSA-N

InChI

1S/C12H9F/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9H

SMILES string

Fc1ccccc1-c2ccccc2

assay

96%

form

solid

bp

248 °C (lit.)

mp

71-74 °C (lit.)

functional group

fluoro
phenyl

Quality Level

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Application

2-Fluorobiphenyl was used as an internal standard for analysis of environmental pollutants in sediments using pressurized liquid extraction and gas chromatography-mass spectrometry. It was used to study the solvent dynamics of 1,2,4,5-tetracyanobenzene/biphenyl derivative radical ion pairs by picosecond absorption spectroscopy. It was also used as a sole carbon and energy source for the biphenyl-degrading bacterium Pseudomonas pseudoalcaligenes KF707.

General description

2-Fluorobiphenyl is a white to off white powder. It is catabolized by C. elegans, yielding hydroxylated products. The metabolism of 2-fluorobiphenyl by hepatic microsomes isolated from control and aroclor 1254-treated rats and pigeons was studied.

Storage Class

11 - Combustible Solids

wgk

WGK 3


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Cormac D Murphy et al.
FEMS microbiology letters, 286(1), 45-49 (2008-07-12)
The biphenyl-degrading bacterium Pseudomonas pseudoalcaligenes KF707 can use 2- and 4-fluorobiphenyl as sole carbon and energy sources. Accumulation of fluorinated catabolites was determined by fluorine-19 nuclear magnetic spectroscopy (19F NMR) and revealed that growth on 4-fluorobiphenyl yielded 4-fluorobenzoate and 4-fluoro-1,2-dihydro-1,2-dihydroxybenzoate
Solvent Effect on the Dynamics of Radical Ion Pair Separation.
Han CH.
Journal of Photoscience, 8(1), 33-37 (2001)
Jessica Amadio et al.
Applied microbiology and biotechnology, 86(1), 345-351 (2009-12-04)
The fungus Cunninghamella elegans is a useful model of human catabolism of xenobiotics. In this paper, the biotransformation of fluorinated biphenyls by C. elegans was investigated by analysis of the culture supernatants with a variety of analytical techniques. 4-Fluorobiphenyl was
Coriness Piñeyro-Ruiz et al.
Frontiers in pediatrics, 8, 202-202 (2020-05-12)
Background & Objective: Hypospadias, characterized by the displacement of the opening of the urethra at any point in the medial-ventral side of the penis, is classified upon severity as mild (Type I) and severe (Type II and Type III) hypospadias.
J T Borlakoglu et al.
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 105(1), 119-125 (1993-05-01)
1. The metabolism of 2-, 3-, 4-bromo-, 2-, 4-chloro-, and 2-fluorobiphenyl by hepatic microsomes isolated from control and Aroclor 1254-treated rats and pigeons was studied. 2. Meta and para as well as dihydroxylated metabolites were detected, but para hydroxylation was

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