146358
1-Ethyl-2-pyrrolidone
98%
Synonym(s):
NEP
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About This Item
Empirical Formula (Hill Notation):
C6H11NO
CAS Number:
Molecular Weight:
113.16
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
220-250-6
Beilstein/REAXYS Number:
107971
MDL number:
Assay:
98%
Form:
liquid
InChI key
ZFPGARUNNKGOBB-UHFFFAOYSA-N
InChI
1S/C6H11NO/c1-2-7-5-3-4-6(7)8/h2-5H2,1H3
SMILES string
CCN1CCCC1=O
assay
98%
form
liquid
refractive index
n20/D 1.465 (lit.)
bp
97 °C/20 mmHg (lit.)
density
0.992 g/mL at 25 °C (lit.)
Quality Level
General description
1-Ethyl-2-pyrrolidone is a transdermal absorption-enhancing compound and mechanism of its effect on multilammellar liposome of stratum corneum lipid has been studied.
Application
1-Ethyl-2-pyrrolidone was used to modify coir fiber (from Cocos nucifera) by photocuring.
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Repr. 1B
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 1
flash_point_f
195.8 °F - Pensky-Martens closed cup
flash_point_c
91 °C - Pensky-Martens closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
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Effect of Pretreatment with Ultraviolet Radiation on the Physicomechanical Properties of Photocured Coir (Cocos nucifera) Fiber with 1-Ethyl-2-Pyrrolidone (1-E-2-P) Monomer.
Khan MA, et al.
Polymer-Plastics Technology and Engineering, 45(4), 487-494 (2006)
Effect of penetration enhancers (pyrrolidone derivatives) on multilamellar liposomes of stratum corneum lipid: a study by UV spectroscopy and differential scanning calorimetry.
Kim C-K, et al.
International Journal of Pharmaceutics, 95(1), 43-50 (1993)
Ajeet Kaushik et al.
Scientific reports, 7, 45663-45663 (2017-04-05)
In this research, we demonstrate cell uptake of magneto-electric nanoparticles (MENPs) through nanoelectroporation (NEP) using alternating current (ac)-magnetic field stimulation. Uptake of MENPs was confirmed using focused-ion-beam assisted transmission electron microscopy (FIB-TEM) and validated by a numerical simulation model. The
Xiaolei Zhu et al.
Aging cell, 16(5), 1073-1082 (2017-08-05)
The accumulation and deposition of beta-amyloid (Aβ) is a key neuropathological hallmark of Alzheimer's disease (AD). Histone deacetylases (HDACs) are promising therapeutic targets for the treatment of AD, while the specific HDAC isoforms associated with cognitive improvement are poorly understood.
Francisco M Pinto et al.
Reproductive biology and endocrinology : RB&E, 8, 104-104 (2010-08-28)
We examined the presence and function of tachykinins and the tachykinin-degrading enzymes neprilysin (NEP) and neprilysin-2 (NEP2) in human spermatozoa. Freshly ejaculated semen was collected from forty-eight normozoospermic human donors. We analyzed the expression of substance P, neurokinin A, neurokinin
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