702153
Hydroxyapatite
nanoparticles, dispersion, 10 wt. % in H2O, <200 nm particle size (BET)
Synonym(s):
Calcium hydroxide phosphate, Calcium hydroxylapatite, Calcium hydroxyphosphate, Nano hydroxyapatatite, Pentacalcium hydroxide triphosphate
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About This Item
Linear Formula:
[Ca5(OH)(PO4)3]x
CAS Number:
Molecular Weight:
502.31
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12352302
MDL number:
Form:
dispersion, nanoparticles
Quality Level
form
dispersion, nanoparticles
contains
≤0.025 wt. % dispersant (non-metal based)
concentration
10 wt. % in H2O
surface area
14.3 m2/g , typical
particle size
<200 nm (BET)
pH
4-6
density
1.038 g/mL at 25 °C
SMILES string
[Ca++].[Ca++].[Ca++].[Ca++].O[Ca+].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O
InChI
1S/5Ca.3H3O4P.H2O/c;;;;;3*1-5(2,3)4;/h;;;;;3*(H3,1,2,3,4);1H2/q5*+2;;;;/p-10
InChI key
XYJRXVWERLGGKC-UHFFFAOYSA-D
General description
Hydroxyapatite(HAP) is an osteoconductive bioceramic material which has uniqueability to form direct bonds with living tissues. It can be easily prepared byvarious techniques such as sol-gel, hydrothermal, multiple emulsion, biomimeticdeposition, and electrodeposition.
Application
Hydroxyapatite can be used as:
- An implant material for bone substitute due to its chemical similarity to the inorganic component of bone and osteo inductive properties.
- A vehicle for gene and drug delivery because of its encapsulation capacity and affinity to several drugs and proteins.
- A pH responsive particulate emulsifier.
Features and Benefits
- Biocompatible
- Osteoconductive
- Stable under physiological conditions
- High mechanical strength
Legal Information
Product of Engi-Mat Co.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Martin P Reichhardt et al.
Life science alliance, 3(4) (2020-02-27)
The scavenger receptor cysteine-rich (SRCR) family of proteins comprises more than 20 membrane-associated and secreted molecules. Characterised by the presence of one or more copies of the ∼110 amino-acid SRCR domain, this class of proteins have widespread functions as antimicrobial
Satyavrata Samavedi et al.
Acta biomaterialia, 9(9), 8037-8045 (2013-06-25)
Calcium phosphate ceramics (CPCs) have been widely used as biomaterials for the regeneration of bone tissue because of their ability to induce osteoblastic differentiation in progenitor cells. Despite the progress made towards fabricating CPCs possessing a range of surface features
W Zhang et al.
Journal of dental research, 92(12), 1136-1141 (2013-10-08)
Stem cell-based bone tissue engineering has been recognized as a new strategy for maxillary sinus floor elevation. More rapid bone formation may enhance this technique when simultaneous dental implant placement is desired. Adipose tissue-derived stem cells (ADSCs) and bone marrow