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Merck

N27802

4-Nitro-3-(trifluoromethyl)phenol

99% (GC)

Synonym(s):

Lamprecide, TFM

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About This Item

Linear Formula:
O2NC6H3(CF3)OH
CAS Number:
88-30-2
Molecular Weight:
207.11
NACRES:
NA.22
PubChem Substance ID:
24897596
UNSPSC Code:
12352100
EC Number:
201-818-2
MDL number:
MFCD00014714

Product Name

4-Nitro-3-(trifluoromethyl)phenol, 99% (GC)

InChI key

ZEFMBAFMCSYJOO-UHFFFAOYSA-N

InChI

1S/C7H4F3NO3/c8-7(9,10)5-3-4(12)1-2-6(5)11(13)14/h1-3,12H

SMILES string

Oc1ccc(c(c1)C(F)(F)F)[N+]([O-])=O

assay

99% (GC)

form

powder

bp

135-138 °C/0.01 mmHg (lit.)

mp

76-79 °C (lit.)

Quality Level

100

Gene Information

human ... CA2(760)

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GHS07

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Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCV3652
MKCQ9066
MKCS5906
MKCH2195
MKBX5239V

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Oana Birceanu et al.
Aquatic toxicology (Amsterdam, Netherlands), 94(4), 265-274 (2009-09-01)
Although the pesticide, 3-trifluoromethyl-4-nitrophenol (TFM), has been extensively used to control invasive sea lamprey (Petromyzon marinus) populations in the Great Lakes, it is surprising that its mechanism(s) of toxicity is unresolved. A better knowledge of the mode of toxicity of
Terrance D Hubert et al.
Journal of agricultural and food chemistry, 53(13), 5342-5346 (2005-06-23)
Rainbow trout (Oncorhyncus mykiss) were exposed to the (14)C-labeled lampricide 3-trifluoromethyl-4-nitrophenol (TFM) (2.1 mg/L) or niclosamide (0.055 mg/L) in an aerated static water bath for 24 h. Fish were sacrificed immediately after exposure. Subsamples of skin-on muscle tissue were analyzed
Oana Birceanu et al.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 153(3), 342-349 (2010-12-22)
The toxicity of 3-trifluoromethyl-4-nitrophenol (TFM) appears to be due to a mismatch between ATP supply and demand in lamprey, depleting glycogen stores and starving the nervous system of ATP. The cause of this TFM-induced ATP deficit is unclear. One possibility
Luís B Sardinha et al.
Pediatric obesity, 12(5), 373-379 (2016-06-04)
The amount of time children spend in sedentary behaviours may have adverse health effects. To examine the substitution effects of displacing a fixed duration of sedentary time with physical activity (PA) on children's body composition. We included 386 children (197
L V Magnussen et al.
Andrology, 5(5), 946-953 (2017-09-16)
The purpose of the study was to evaluate whether testosterone replacement therapy improves muscle mechanical and physical function in addition to increasing lean leg mass and total lean body mass in aging men with type 2 diabetes and lowered bio-available
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