Skip to Content
Merck

264101

Deoxycholic Acid sodium

An ionic detergent for the solubilization of membrane-bound proteins.

Synonym(s):

Sodium deoxycholate, 3α,12α-Dihydroxy-5β-cholanic acid sodium salt, 7-Deoxycholic acid sodium salt, Desoxycholic acid sodium salt

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C24H39NaO4
CAS Number:
Molecular Weight:
414.55
NACRES:
NA.21
UNSPSC Code:
12161902
Beilstein/REAXYS Number:
3581950
MDL number:
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


Quality Level

description

Merck USA index - 14, 2899

assay

≥96% (TLC)

form

powder

mol wt

micellar avg mol wt 1200-5000, micellar wt 1700-4200

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, desiccated (hygroscopic)

aggregation number

3-12, 4 - 10

color

white to off-white

pKa 

6.2

CMC

2-6 mM (20-25°C), 4 - 8 mM

solubility

H2O: 2%, clear, colorless

cation traces

heavy metals: ≤20.0 ppm

HLB

16

shipped in

ambient

storage temp.

15-25°C

SMILES string

[Na+].[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@H]([C@H](C)CCC([O-])=O)[C@@]4(C)[C@@H](O)C[C@]3([H])[C@@]1(C)CC[C@@H](O)C2

InChI

1S/C24H40O4.Na/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;/m1./s1

InChI key

FHHPUSMSKHSNKW-SMOYURAASA-M

General description

An ionic detergent for the solubilization of membrane-bound proteins (aggregation number: 4-10; CMC: 4-8 mM; micellar weight: 1700-4200; pKa 6.2). Reported to induce tyrosine phosphorylation of β-catenin and its subsequent translocation to the nucleus, promoting activation of β-catenin signaling (effective concentration 5-50 µM).

Other Notes

Pai, R., et al. 2004. Mol. Biol. Cell15 2156.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Harmful (C)


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library