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Merck

33700

Danofloxacin

VETRANAL®, analytical standard

Synonym(s):

Advocin®

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About This Item

Empirical Formula (Hill Notation):
C19H20FN3O3
CAS Number:
112398-08-0
Molecular Weight:
357.38
NACRES:
NA.24
PubChem Substance ID:
329754635
UNSPSC Code:
41116107
MDL number:
MFCD00864910

Product Name

Danofloxacin, VETRANAL®, analytical standard

Quality Level

100

InChI

1S/C19H20FN3O3/c1-21-7-12-4-11(21)8-22(12)17-6-16-13(5-15(17)20)18(24)14(19(25)26)9-23(16)10-2-3-10/h5-6,9-12H,2-4,7-8H2,1H3,(H,25,26)/t11-,12-/m0/s1

SMILES string

CN1C[C@@H]2C[C@H]1CN2c3cc4N(C=C(C(O)=O)C(=O)c4cc3F)C5CC5

InChI key

QMLVECGLEOSESV-RYUDHWBXSA-N

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

Advocin is a registered trademark of Pfizer, Inc.
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazard
GHS08

signalword

Warning

hcodes

H373,H412

Hazard Classifications

Aquatic Chronic 3 - STOT RE 2

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM9147
BCCM2130
BCCD0344
BCBW6022

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Ana García-Galán et al.
Pathogens (Basel, Switzerland), 9(7) (2020-07-11)
Mycoplasma bovis is an important bovine pathogen causing pneumonia, mastitis, and arthritis and is responsible for major economic losses worldwide. In the absence of an efficient vaccine, control of M. bovis infections mainly relies on antimicrobial treatments, but resistance is
Andrea Speltini et al.
Analytical and bioanalytical chemistry, 404(5), 1565-1569 (2012-07-21)
Here we describe the extraction from soil of the major photo-transformation products (PTPs) of enrofloxacin (ENR) and danofloxacin (DAN), two fluoroquinolones (FQs) widely used in veterinary medicine and of growing environmental concern, because their PTPs have been shown to retain
Michela Sturini et al.
Water research, 46(17), 5575-5582 (2012-08-21)
The widespread presence of fluoroquinolone antibiotics (FQs) in natural ecosystems is a health hazard for humans and other living organisms. The role of sunlight in degrading FQs present in environmental waters has been studied. In particular, the photodegradation of four
Pekka Juntunen et al.
Veterinary microbiology, 150(3-4), 322-330 (2011-03-15)
Effects of danofloxacin or consecutive fluoroquinolone and macrolide treatments on resistance development in Campylobacter have remained uncharacterised. Therefore we analysed the development of resistance in porcine Campylobacter coli before and after danofloxacin and tylosin treatments at a farrowing farm. Danofloxacin-treated
Mariana Ballent et al.
Veterinary journal (London, England : 1997), 192(3), 422-427 (2011-11-15)
The impact of an efflux pump-related interaction between ivermectin and danofloxacin on their intestinal transport (ex vivo) and disposition kinetics (in vivo) was assessed. Eighteen male Corriedale sheep were randomly assigned to one of three groups. Animals in Group A
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