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Merck

G5767

D-(+)-Glucose

ACS reagent

Synonym(s):

Dextrose

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About This Item

Empirical Formula (Hill Notation):
C6H12O6
CAS Number:
50-99-7
Molecular Weight:
180.16
PubChem Substance ID:
24895228
UNSPSC Code:
12352201
MDL number:
MFCD00063774
NACRES:
NA.21
EC Number:
200-075-1
Beilstein/REAXYS Number:
1724615

Product Name

D-(+)-Glucose, ACS reagent

InChI

1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1

InChI key

WQZGKKKJIJFFOK-DVKNGEFBSA-N

SMILES string

OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O

biological source

wheat

grade

ACS reagent

form

powder

optical activity

[α]25/D +52.5 to +53.0°(lit.)

impurities

Starch, passes test
≤0.002 meq/g Titratable acid
≤0.005% Insoluble matter

ign. residue

≤0.02%

loss

≤0.2% loss on drying, 105°C

color

colorless

mp

150-152 °C (lit.)

anion traces

chloride (Cl-): ≤0.01%
sulfate, sulfite (as SO42-): ≤0.005%

cation traces

Fe: ≤5 ppm
heavy metals: ≤5 ppm (by ICP-OES)

storage temp.

room temp

Quality Level

200

Gene Information

human ... PYGM(5837)

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Application

D-(+)-Glucose has been used:
  • as a supplement in Dulbecco′s phosphate-buffered saline (DPBS) for standardized serum bactericidal assay (SBA) using human complement
  • as a component in 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES)-buffered Tyrode′s solution to treat the excised diaphragmatic specimens to assess the effect of osmolarity changes on the intrinsic lymphatic pumping mechanism
  • to study the effect of restoring circulating glucose content in insulin-responsive neurons of rats
  • for oral glucose tolerance tests (OGTTs)

Biochem/physiol Actions

Glucose, the universal energy source for all human cells, is the vital precursor for the production and conversion of several downstream carbohydrates. The uptake of glucose is a key indicator of cellular energy metabolism. Glucose infusion can block the release of oxytocin and vasopressin by insulin-induced hypoglycemia in humans.

General description

D-glucose, an aldohexose, possesses four chiral carbon atoms. It is an important product obtained from starch hydrolyzed by acid and/or enzymes.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Preparation Note

The material may produce a yellowish solution if prepared at a higher concentration than 2 g + 15mL.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000519495
0000519495
BCCP0321
0000511126
0000511126

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Ragadeepthi Tunduguru et al.
Biochemical pharmacology, 92(2), 380-388 (2014-09-10)
Skeletal muscle accounts for ∼ 80% of postprandial glucose clearance, and skeletal muscle glucose clearance is crucial for maintaining insulin sensitivity and euglycemia. Insulin-stimulated glucose clearance/uptake entails recruitment of glucose transporter 4 (GLUT4) to the plasma membrane (PM) in a
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Carvacrol, an aromatic terpenic compound, known to be antimicrobial was grafted onto gold surfaces via two strategies based on newly-synthesized cross-linkers involving either an ester bond which can be cleaved by microbial esterases, or a covalent ether link. Surface functionalizations
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The New England journal of medicine, 370(6), 533-542 (2014-02-07)
Congenital disorders of glycosylation are genetic syndromes that result in impaired glycoprotein production. We evaluated patients who had a novel recessive disorder of glycosylation, with a range of clinical manifestations that included hepatopathy, bifid uvula, malignant hyperthermia, hypogonadotropic hypogonadism, growth
Yu-ting Alex Chiang et al.
American journal of physiology. Endocrinology and metabolism, 306(7), E707-E722 (2013-12-26)
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