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Merck

O1378

Oxycodone hydrochloride

analytical standard

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About This Item

Empirical Formula (Hill Notation):
C18H21NO4 · HCl
CAS Number:
Molecular Weight:
351.82
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
204-717-1
MDL number:

Product Name

Oxycodone hydrochloride, analytical standard

InChI key

MUZQPDBAOYKNLO-RKXJKUSZSA-N

InChI

1S/C18H21NO4.ClH/c1-19-8-7-17-14-10-3-4-12(22-2)15(14)23-16(17)11(20)5-6-18(17,21)13(19)9-10;/h3-4,13,16,21H,5-9H2,1-2H3;1H/t13-,16+,17+,18-;/m1./s1

SMILES string

Cl.[H][C@@]12Oc3c(OC)ccc4C[C@H]5N(C)CC[C@@]1(c34)[C@@]5(O)CCC2=O

grade

analytical standard

drug control

USDEA Schedule II; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
kontrollierte Droge in Deutschland

Quality Level

Gene Information

human ... OPRM1(4988)

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

μ and κ opioid receptor agonist.

General description

Oxycodone hydrochloride is an analgesic drug, which is generally used in cancer treatment since it can reduce the pain induced during the treatment.

Legal Information

German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.

English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral - STOT SE 3

target_organs

Central nervous system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Rachel E Martin et al.
eNeuro, 8(4) (2021-07-28)
Opioid drugs are increasingly being prescribed to pregnant women. Such compounds can also bind and activate opioid receptors in the fetal brain, which could lead to long-term brain and behavioral disruptions. We hypothesized that maternal treatment with oxycodone (OXY), the
Self-assembly of thermally responsive nanoparticles of a genetically encoded peptide polymer by drug conjugation.
Jonathan R McDaniel et al.
Angewandte Chemie (International ed. in English), 52(6), 1683-1687 (2013-01-03)
Clinical observations on safety and efficacy of OxyContin? administered by rectal route in treating cancer related pain
Li G-C, et al.
Asian Pacific Journal of Cancer Prevention, 12, 2477-2478 (2011)
M Soledad Cepeda et al.
The journal of pain : official journal of the American Pain Society, 14(2), 158-164 (2012-12-21)
Obtaining opioids from multiple prescribers, known as doctor shopping, is 1 example of opioid abuse and diversion. The dual mechanism of action of tapentadol could make tapentadol less likely to be abused than other opioids. The aim of this retrospective
M Kokki et al.
British journal of anaesthesia, 112(1), 133-140 (2013-10-18)
Despite being increasingly used for pain management, only two studies, with controversial results, have evaluated the epidural use of oxycodone. Twenty-four women, aged 26-64 yr, undergoing elective gynaecological surgery were enrolled in this randomized, double-blinded, parallel group study. The subjects

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