S1429

Sodium acetate

Name: Sodium acetate
Brand: SIAL

meets USP testing specifications, anhydrous

Synonym(s):

Acetic acid sodium salt

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About This Item

Linear Formula:

CH₃COONa

CAS Number:

127-09-3

Molecular Weight:

82.03

NACRES:

NA.21

PubChem Substance ID:

24899479

eCl@ss:

39021906

UNSPSC Code:

12352300

EC Number:

204-823-8

MDL number:

MFCD00012459

Beilstein/REAXYS Number:

3595639

Product Name

Sodium acetate, meets USP testing specifications, anhydrous

InChI key

VMHLLURERBWHNL-UHFFFAOYSA-M

InChI

1S/C2H4O2.Na/c1-2(3)4;/h1H3,(H,3,4);/q;+1/p-1

SMILES string

[Na+].CC([O-])=O

grade

anhydrous

agency

USP/NF
meets USP testing specifications

assay

99-101% dry basis

form

solid

autoignition temp.

1112 °F

pH

8.5-9.9 (25 °C, 246 g/L)

pKa

4.76 (acetic acid)

mp

>300 °C (dec.) (lit.)

solubility

soluble 246 g/L at 20 °C (completely)

application(s)

pharmaceutical (small molecule)

Quality Level

200

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Related Categories

Biochemicals

Biological Buffers

Chemistry & Biochemicals

Application

Sodium acetate (SA) has been used to increase hepatic acetyl- coenzyme A in caloric restricted rats.

General description

Sodium acetate (SA) exhibits antimicrobial and antioxidant properties. It is used as an exchange-fluid buffer in hemodialysis. SA acts as an a alkalinizing agent and its continuous intravenous (IV) infusion causes salicylate intoxication.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Sodium Acetate as an Alkalinizing Agent for Salicylate Intoxication: A Case Report

Groke SF, et al.

Journal of Clinical Toxicology (2015)

Enhancement of in-vitro human interleukin-1 production by sodium acetate

Bingel M, et al.

Lancet, 329(8523), 14-16 (1987)

Antimicrobial and antioxidant effects of sodium acetate, sodium lactate, and sodium citrate in refrigerated sliced salmon

Sallam KI, et al.

Food Control, 18(5), 566-575 (2007)

Mechanisms by which a very-low-calorie diet reverses hyperglycemia in a rat model of type 2 diabetes

Perry RJ, et al.

Cell Metabolism, 27(1), 210-217 (2018)

Adaptive Modifications of Muscle Phenotype in High-Altitude Deer Mice Are Associated with Evolved Changes in Gene Regulation.

Graham R Scott et al.

Molecular biology and evolution, 32(8), 1962-1976 (2015-04-09)

At high-altitude, small mammals are faced with the energetic challenge of sustaining thermogenesis and aerobic exercise in spite of the reduced O2 availability. Under conditions of hypoxic cold stress, metabolic demands of shivering thermogenesis and locomotion may require enhancements in

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