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About This Item
Empirical Formula (Hill Notation):
C25H27IN2S2
CAS Number:
Molecular Weight:
546.53
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352116
MDL number:
Quality Level
assay
≥98.0% (TLC)
form
powder
mp
245 °C (dec.) (lit.)
solubility
DMF: soluble
fluorescence
λex 500 nm; λem 705 nm in DMF
suitability
suitable for fluorescence
SMILES string
[I-].CCCN1C(\Sc2ccccc12)=C\C=C\C=C\c3sc4ccccc4[n+]3CCC
InChI
1S/C25H27N2S2.HI/c1-3-18-26-20-12-8-10-14-22(20)28-24(26)16-6-5-7-17-25-27(19-4-2)21-13-9-11-15-23(21)29-25;/h5-17H,3-4,18-19H2,1-2H3;1H/q+1;/p-1
InChI key
GDEURKKLNUGTDA-UHFFFAOYSA-M
Application
3,3′-Dipropylthiadicarbocyanine iodide [DiSC3(5)] is used as a fluorogenic probe to detect and measure changes in transmembrane potential or configuration induced by membrane altering agents.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Other Notes
Transmembrane potential measurements
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Wen Ma et al.
Journal of proteomics, 150, 242-251 (2016-10-25)
Daptomycin (DAP) is a novel lipopeptide antibiotic which exhibits excellent antibacterial activity against most clinically relevant Gram-positive bacteria, but the DAP-targeting protein molecules against host bacterial infection are far from clear. In order to discover bacterial protein response to DAP
Min Kyoung Shin et al.
Antibiotics (Basel, Switzerland), 9(7) (2020-07-28)
The prevalence of antibiotic-resistant bacteria has become an immediate threat to public health. Antimicrobial peptides are attracting attention as a new source of antibiotics due to their ability to prevent drug-resistances with fewer side effects. Spider venom is composed of
M Síp et al.
Journal of photochemistry and photobiology. B, Biology, 4(3), 321-328 (1990-01-01)
The mechanism of carbocyanine dye diS-C3-(5) fluorescence intensity variations with transmembrane potential changes has been studied using time-resolved fluorescence spectroscopy. Clear evidence is given of the transmembrane-potential-dependent partition of the dye among various sites with different fluorescence lifetimes. It was
