G6750

α-D-Glucose 1-phosphate dipotassium salt hydrate

Name: α-<SC>D</SC>-Glucose 1-phosphate dipotassium salt hydrate
Brand: SIGMA

≥99% (HPLC), BioXtra

Synonym(s):

α-D-Glucopyranose 1-phosphate, Cori ester

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About This Item

Empirical Formula (Hill Notation):

C₆H₁₁K₂O₉P · xH₂O

CAS Number:

1233690-06-6

Molecular Weight:

336.32 (anhydrous basis)

MDL number:

MFCD00149436

UNSPSC Code:

12352201

PubChem Substance ID:

24895267

NACRES:

NA.25

Product Name

α-D-Glucose 1-phosphate dipotassium salt hydrate, ≥99% (HPLC), BioXtra

SMILES string

[K+].[K+].[H]O[H].OC[C@H]1O[C@H](OP([O-])([O-])=O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H13O9P.2K.H2O/c7-1-2-3(8)4(9)5(10)6(14-2)15-16(11,12)13;;;/h2-10H,1H2,(H2,11,12,13);;;1H2/q;2*+1;/p-2/t2-,3-,4+,5-,6-;;;/m1.../s1

InChI key

VOQGDSVKCMGEFO-FBNUBEQJSA-L

biological source

synthetic

product line

BioXtra

assay

≥99% (HPLC)

form

powder

impurities

glucose and starch, essentially free

color

white to off-white

solubility

water: 50 mg/mL, clear, colorless

cation traces

K: 20.4-26.1% (ICP)

storage temp.

−20°C

Quality Level

200

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Related Categories

Biochemicals

Carbohydrates for Biochemical Research

Cell Culture Supplements & Reagents

Chemical Biology

Chemistry & Biochemicals

General description

α-D-Glucose 1-phosphate is the α-anomeric form of glucose which contains a phosphate group on the primary carbon. It can be converted into the deoxysugar CDP-glucose by the enzyme α-D-Glucose-1-phosphate cytidylyltransferase.

Other Notes

Formerly listed as Grade V.

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Molecular structure of alpha-D-glucose-1-phosphate cytidylyltransferase from Salmonella typhi.

Nicole M Koropatkin et al.

The Journal of biological chemistry, 279(42), 44023-44029 (2004-08-05)

Dideoxysugars, which display biological activities ranging from mediating cell-cell interactions to serving as components in some antibiotics, are synthesized in various organisms via complex biochemical pathways that begin with the attachment of alpha-D-glucose 1-phosphate to either CTP or dTTP. Here

Identification of a novel UDP-sugar pyrophosphorylase with a broad substrate specificity in Trypanosoma cruzi.

Ting Yang et al.

The Biochemical journal, 429(3), 533-543 (2010-05-21)

The diverse types of glycoconjugates synthesized by trypanosomatid parasites are unique compared with the host cells. These glycans are required for the parasite survival, invasion or evasion of the host immune system. Synthesis of those glycoconjugates requires a constant supply

Earl Sutherland (1915-1974) [corrected] and the discovery of cyclic AMP.

Stanley A Blumenthal

Perspectives in biology and medicine, 55(2), 236-249 (2012-05-31)

In 1945, Earl Sutherland (1915-1974) [corrected] and associates began studies of the mechanism of hormone-induced glycogen breakdown in the liver. In 1956, their efforts culminated in the identification of cyclic AMP, an ancient molecule generated in many cell types in

The amino acid sequences in the C-terminal region of glucose-1-phosphate thymidylyltransferases determine their soluble expression in Escherichia coli.

Bijay Singh et al.

Protein engineering, design & selection : PEDS, 25(4), 179-187 (2012-02-16)

Two similar genes, dnmL and rmbA in Streptomyces peucetius, which encode for glucose-1-phosphate (G-1-P) thymidylyltransferases were expressed in Escherichia coli under similar conditions. While RmbA was expressed in soluble form, DnmL was found as insoluble aggregates in inclusion bodies. The

Chitosan-based thermosensitive hydrogel as a promising ocular drug delivery system: preparation, characterization, and in vivo evaluation.

Xingwei Chen et al.

Journal of biomaterials applications, 27(4), 391-402 (2011-07-14)

The purpose of this study was to evaluate the feasibility of in situ thermosensitive hydrogel based on chitosan in combination with disodium α-d-Glucose 1-phosphate (DGP) for ocular drug delivery system. Aqueous solution of chitosan/DGP underwent sol-gel transition as temperature increased

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