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Merck

G7000

α-D-Glucose 1-phosphate disodium salt hydrate

≥97% (Enzymatic Purity, anhydrous)

Synonym(s):

α-D-Glucopyranose 1-phosphate, Cori ester

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About This Item

Linear Formula:
C6H11O9PNa2 · xH2O
CAS Number:
56401-20-8
Molecular Weight:
304.10 (anhydrous basis)
NACRES:
NA.25
PubChem Substance ID:
24895281
UNSPSC Code:
12352201
EC Number:
260-154-1
MDL number:
MFCD00150837

Product Name

α-D-Glucose 1-phosphate disodium salt hydrate, ≥97% (Enzymatic Purity, anhydrous)

InChI key

YWAUQXHOCBBYLP-FBNUBEQJSA-L

InChI

1S/C6H13O9P.2Na.H2O/c7-1-2-3(8)4(9)5(10)6(14-2)15-16(11,12)13;;;/h2-10H,1H2,(H2,11,12,13);;;1H2/q;2*+1;/p-2/t2-,3-,4+,5-,6-;;;/m1.../s1

SMILES string

[Na+].[Na+].[H]O[H].OC[C@H]1O[C@H](OP([O-])([O-])=O)[C@H](O)[C@@H](O)[C@@H]1O

biological source

synthetic

assay

≥97% (Enzymatic Purity, anhydrous)

form

powder

impurities

≤0.1 mol % glucose
≤0.5 mol % α-D-glucose 1,6-diphosphate

color

white

solubility

water: 50 mg/mL, clear, colorless

cation traces

Na: 13.5-16.7% (anhydrous)

application(s)

agriculture

storage temp.

−20°C

Quality Level

200

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Biochem/physiol Actions

Glucose-1-phosphate (G1P) is produced from glycogen during glycogenolysis by the actions of glycogen phosphorylase. Conversion to glucose-6-phosphate (G6P) by phosphoglucomutase allows for entry of the glucose molecule into metabolic pathways such as glycolysis. During glycogenesis, G6P is converted to G1P by the actions of phosphoglucose isomerase.

General description

α-D-Glucose 1-phosphate is converted into D-glucose-6-phosphate by the enzyme phosphoglucomutase.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Preparation Note

Prepared by a modification of the procedure of McCready, R.M., et al., J. Am. Chem. Soc., 66, 560 (1944).

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000522212
0000522212
0000484482
0000484478
0000484481

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Fumiaki Ito et al.
Biochimica et biophysica acta, 1844(4), 759-766 (2014-02-05)
The archaeal non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (GAPN, EC 1.2.1.9) is a highly allosteric enzyme activated by glucose 1-phosphate (Glc1P). Recent kinetic analyses of two GAPN homologs from Sulfolobales show different allosteric behaviors toward the substrate glyceraldehyde-3-phosphate (GAP) and the allosteric effector
Rickard Olsson et al.
Environmental science & technology, 46(1), 285-291 (2011-11-23)
Esters of phosphoric acid constitute a sizable fraction of the total phosphorus supply in the environment and thus play an important role in the global phosphorus cycle. Enzymatic hydrolysis of these esters to produce orthophosphate is often a required reaction
Rickard Olsson et al.
Langmuir : the ACS journal of surfaces and colloids, 26(24), 18760-18770 (2010-11-20)
Adsorption, desorption, and precipitation reactions at environmental interfaces govern the fate of phosphorus in terrestrial and aquatic environments. Typically, a substantial part of the total pool of phosphorus consists of organophosphate, and in this study we have focused on the
Xingwei Chen et al.
Journal of biomaterials applications, 27(4), 391-402 (2011-07-14)
The purpose of this study was to evaluate the feasibility of in situ thermosensitive hydrogel based on chitosan in combination with disodium α-d-Glucose 1-phosphate (DGP) for ocular drug delivery system. Aqueous solution of chitosan/DGP underwent sol-gel transition as temperature increased
Kacper Piotr Kaminski et al.
PloS one, 7(12), e51248-e51248 (2013-01-04)
Glucose-6-phosphate is imported into the amyloplast of potato tubers and thought to constitute the precursor for starch synthesis in potato tubers. However, recently it was shown that glucose-1-phosphate can also be imported into the amyloplast and incorporated into starch via
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