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Merck

H0536

Hepatocyte Growth Factor Receptor (c-Met)/Fc Chimera human

>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

Synonym(s):

HGF Receptor (c-Met)

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.32
MDL number:
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biological source

human

Quality Segment

recombinant

expressed in NSO cells

assay

>95% (SDS-PAGE)

form

lyophilized powder

potency

0.1-5 ng/mL

mol wt

calculated mol wt 129 kDa

packaging

pkg of 100 μg

storage condition

avoid repeated freeze/thaw cycles

impurities

endotoxin, tested

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... MET(4233)

Biochem/physiol Actions

Heterodimeric transmembrane glycoprotein with binding capacity for c-Met. Activation of this receptor has been correlated with induction of the Ras pathway.

Physical form

Lyophilized from 0.2 μm filtered solution in phosphate buffered saline containing 5 mg bovine serum albumin.

Analysis Note

The biological activity is measured by its ability to bind human HGF.

Other Notes

Extracellular domain of c-Met fused to the C-terminal 6X histidine-tagged Fc region of human IgG1.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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