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Merck

481181

Silver(I) sulfadiazine

98%

Synonym(s):

Silver sulfadiazine, Sulfadiazine silver

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About This Item

Empirical Formula (Hill Notation):
C10H9AgN4O2S
CAS Number:
Molecular Weight:
357.14
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12352302
EC Number:
244-834-5
MDL number:
Assay:
98%
Form:
powder
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Quality Level

assay

98%

form

powder

reaction suitability

core: silver

mp

285 °C (dec.) (lit.)

application(s)

PEM fuel cells
material synthesis precursor

SMILES string

Nc1ccc(cc1)S(=O)(=O)N([Ag])c2ncccn2

InChI

1S/C10H9N4O2S.Ag/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10;/h1-7H,11H2;/q-1;+1

InChI key

UEJSSZHHYBHCEL-UHFFFAOYSA-N

Application

Silver(I) sulfadiazine (AgSD) is popularly used for treating second-degree burn wounds as it acts as an antimicrobial agent and prevents infections. Silver sulfadiazine-impregnated polyurethane (PU) foam, chitosan/chondroitin sulfate films may be used for wound dressing.


Storage Class

11 - Combustible Solids

wgk

WGK 2



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Silver sulfadiazine loaded chitosan/chondroitin sulfate films for a potential wound dressing application
Fajardo AR, et al.
Materials Science & Engineering. C, Materials For Biological Applications, 33(2), 588-595 (2013)
Steven L Percival et al.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, 20(5), 647-657 (2012-09-19)
Both chronic and acute dermal wounds are susceptible to infection due to sterile loss of the innate barrier function of the skin and dermal appendages, facilitating the development of microbial communities, referred to as biofilms, within the wound environment. Microbial
Clinical experience with silver sulfadiazine, a new topical agent for control of pseudomonas infections in burns
Stanford, W, et al.
The Journal of Trauma and Acute Care Surgery, 9(5), 377-388 (1969)