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Merck

A8056

3-Amino-1,2,4-triazole

powder, ≥95% (TLC)

Synonym(s):

1,2,4-Triazol-3-amine, 3-AT, Amitrol

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About This Item

Empirical Formula (Hill Notation):
C2H4N4
CAS Number:
61-82-5
Molecular Weight:
84.08
NACRES:
NA.83
PubChem Substance ID:
24891312
UNSPSC Code:
12352204
EC Number:
200-521-5
MDL number:
MFCD00005230
Beilstein/REAXYS Number:
107687

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Product Name

3-Amino-1,2,4-triazole, ≥95% (TLC)

InChI

1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)

SMILES string

Nc1nc[nH]n1

InChI key

KLSJWNVTNUYHDU-UHFFFAOYSA-N

biological source

synthetic (organic)

assay

≥95% (TLC)

form

powder

potency

30 μM Ki

mp

150-153 °C (lit.)

solubility

water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

storage temp.

−20°C

Quality Level

200

General description

3-Amino-1,2,4-triazole is a herbicide effective against weeds especially bermuda and quack grass. It enters plant circulation through roots and is majorly present in the meristem. 3-Amino-1,2,4-triazole inhibits chlorophyll synthesis resulting in chlorotic leaves and albino plants. In addition, it also affects the growth of the plants. It is exploited to destroy unwanted weeds. It is synthesized from aminoguanidine formate and corresponds to a molecular weight of 84 Da.

Application

3-Amino-1,2,4-triazole has been used:
  • as an organelle-specific perturbant in human embryonic kidney (HEK293T) cells
  • as histidine biosynthesis inhibitor in medium for screening co-transformants from yeast two-hybrid interactions
  • for preservation of midgut sample from honey bee
  • for the determination of tryptophan in proteins.

pictograms

Health hazardEnvironment
GHS08,GHS09

signalword

Warning

Hazard Classifications

Aquatic Chronic 2 - Repr. 2 - STOT RE 2

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
MKCZ8061
WXBF5315V
WXBF1543V
WXBD8112V
WXBD6049V

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The Biology and Control of Weeds in Sugarcane, 88-88 (2012)
Aarthi Putarjunan et al.
Nature plants, 5(7), 742-754 (2019-06-27)
Cell fate in eukaryotes is controlled by mitogen-activated protein kinases (MAPKs) that translate external cues into cellular responses. In plants, two MAPKs-MPK3 and MPK6-regulate diverse processes of development, environmental response and immunity. However, the mechanism that bridges these shared signalling
Understanding organellar protein folding capacities and assessing their pharmacological modulation by small molecules
Sharma R, et al.
European Journal of Cell Biology, 97(2), 114-125 (2018)
Thermoanalytical study of the pesticide 3-amino-1, 2, 4-triazole
Sanchez-Soto P, et al.
Journal of Thermal Analysis and Calorimetry, 45(5), 1189-1197 (1995)
Nt-RhoGDI2 regulates Rac/Rop signaling and polar cell growth in tobacco pollen tubes
Klahre U, et al.
The Plant Journal, 46(6), 1018-1031 (2006)
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Product Information Sheet - A8056

Product Information Sheet

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