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Merck

258385

Protoporphyrin IX disodium salt

≥90% (HPLC)

Synonym(s):

3,7,12,17-Tetramethyl-8,13-divinyl-2,18-porphinedipropionic acid disodium salt, Depocolin-S, Ooporphyrin disodium salt

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About This Item

Empirical Formula (Hill Notation):
C34H32N4Na2O4
CAS Number:
Molecular Weight:
606.62
UNSPSC Code:
12352103
NACRES:
NA.23
PubChem Substance ID:
EC Number:
256-815-9
Beilstein/REAXYS Number:
5227034
MDL number:
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Quality Level

assay

≥90% (HPLC)

form

powder

λmax

406 nm

storage temp.

2-8°C

SMILES string

[Na+].[Na+].Cc1c(CCC([O-])=O)c2cc3[nH]c(cc4nc(cc5[nH]c(cc1n2)c(C=C)c5C)c(C=C)c4C)c(C)c3CCC([O-])=O

InChI

1S/C34H34N4O4.2Na/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;;/h7-8,13-16,36-37H,1-2,9-12H2,3-6H3,(H,39,40)(H,41,42);;/q;2*+1/p-2/b25-13-,26-13-,27-14-,28-15-,29-14-,30-15-,31-16-,32-16-;;

InChI key

JZRNDUPVNXWZDY-HXFTUNQESA-L

Application

Protoporphyrin disodium salt (PpIX) was used as a dye content for fluorescence spectroscopic characterization in a study. The cytotoxic effect of PpIX on sarcoma 180 solid tumors cells was reported in a study.


Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Sonodynamic effects of protoporphyrin IX disodium salt on isolated sarcoma 180 cells
Liu Q, et al.
Ultrasonics, 45(1-4), 56-60 (2006)
Fluorescence spectroscopic characterization of salivary metabolites of oral cancer patients.
Yuvaraj M, et al.
Journal of Photochemistry and Photobiology. B, Biology, 130, 153-160 (2014)
Kiwamu Takahashi et al.
Anticancer research, 33(7), 2861-2866 (2013-06-20)
5-Aminolevulinic acid (ALA) is a precursor of heme. ALA is used as a photosensitive substance in photodynamic diagnosis (PDD) and photodynamic therapy (PDT) because heme metabolism is abnormal in tumor cells and a photosensitive metabolite of heme synthesis from ALA