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Merck

V-011

Retinol solution

100 μg/mL ± 25% (Refer to COA) (Ethanol with 0.1% (w/v) BHT), ampule of 1 mL, reference material, Cerilliant®

Synonym(s):

Retinol solution, 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)-2,4,6,8-nonatetraen-1-ol, Axerophthol, Vitamin A alcohol solution, Vitamin A1, all-trans-Retinol

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About This Item

Empirical Formula (Hill Notation):
C20H30O
CAS Number:
68-26-8
Molecular Weight:
286.45
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329828922
MDL number:
MFCD00001552
Beilstein/REAXYS Number:
403040

Product Name

Retinol solution, 100 μg/mL ± 25% (Refer to COA) (Ethanol with 0.1% (w/v) BHT), ampule of 1 mL, reference material, Cerilliant®

InChI key

FPIPGXGPPPQFEQ-OVSJKPMPSA-N

SMILES string

CC(=C/CO)\C=C\C=C(C)\C=C\C1=C(C)CCCC1(C)C

InChI

1S/C20H30O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,21H,7,10,14-15H2,1-5H3/b9-6+,12-11+,16-8+,17-13+

grade

reference material

form

liquid

feature

(Snap-N-Shoot®)
 (Snap-N-Spike®)

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

100 μg/mL ± 25% (Refer to COA) (Ethanol with 0.1% (w/v) BHT)

application(s)

clinical testing
clinical testing

format

single component solution

storage temp.

−70°C

Quality Level

200

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Features and Benefits

  • Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation
  • Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
  • Rigorously tested through real-time stability studies to ensure accuracy and shelf life
  • Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
  • Flame sealed under argon into ampoules for long-term shelf life
  • Offered in a convenient, DEA-exempt format to improve laboratory efficiency

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

hcodes

H225,H319

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

57.2 °F

flash_point_c

14.0 °C

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Certificates of Analysis (COA)

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Sarmila Mazumder et al.
Lancet (London, England), 385(9975), 1333-1342 (2014-12-17)
Vitamin A supplementation in children aged 6 months to 5 years has been shown to reduce mortality. The efficacy of neonatal supplementation with vitamin A to reduce mortality in the first 6 months of life is plausible but not established.
Gretchen A Stevens et al.
The Lancet. Global health, 3(9), e528-e536 (2015-08-16)
Vitamin A deficiency is a risk factor for blindness and for mortality from measles and diarrhoea in children aged 6-59 months. We aimed to estimate trends in the prevalence of vitamin A deficiency between 1991 and 2013 and its mortality
Malay Rana et al.
Journal of clinical pathology, 67(7), 605-608 (2014-04-09)
Determine the prevalence of fat-soluble vitamin deficiency in children with cystic fibrosis (CF) aged ≤18 years in New South Wales (NSW), Australia, from 2007 to 2010. A retrospective analysis of fat-soluble vitamin levels in children aged ≤18 years who lived in NSW
Emilie Macé et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 23(1), 7-16 (2014-08-07)
Most inherited retinal dystrophies display progressive photoreceptor cell degeneration leading to severe visual impairment. Optogenetic reactivation of retinal neurons mediated by adeno-associated virus (AAV) gene therapy has the potential to restore vision regardless of patient-specific mutations. The challenge for clinical
Giuseppe Zanotti et al.
Vitamins and hormones, 69, 271-295 (2004-06-16)
Retinol-binding protein (RBP) is the retinol-specific transport protein present in plasma. The available crystal structures of different forms of RBP have provided details of the interactions of this binding protein with retinol, retinoids, and transthyretin (TTR, one of the plasma
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