Skip to Content
Merck

GF305

IFN- γ Protein, Human Recombinant Animal Free

The Interferon gamma (or IFN-γ protein) is an acid-labile interferon produced by CD4 & CD8 T lymphocytes as well as activated NK cells. Manufactured using all non-animal reagents.

Synonym(s):

IFN, Interferon Gamma, IFNG, IFN Gamma

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

UNSPSC Code:
12352202
NACRES:
NA.77
eCl@ss:
32160405

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

IFN- γ Protein, Human Recombinant Animal Free, The Interferon gamma (or IFN-γ protein) is an acid-labile interferon produced by CD4 & CD8 T lymphocytes as well as activated NK cells. Manufactured using all non-animal reagents.

assay

>98% (SDS-PAGE and HPLC)

impurities

<0.1 μg/mg protein endotoxin (<1EU/μg)

NCBI accession no.

NM_000619.2

UniProt accession no.

P01579

shipped in

dry ice

Quality Level

100

Related Categories

Analysis Note

Bioactivity assay: Determined by its ability to induce apoptosis in HeLa cells. The expected ED50 for this effect is 5.0-10.0 ng/ml.

General description

Interferon gamma (IFN-γ) is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-γ signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. Additionally, IFN-γ stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-γ species-specific and is biologically active only in human and primate cells. Recombinant human IFN-γ is a 16.7 kDa protein containing 143 amino acid residues.

Physical form

Recombinant animal free human IFN- γ is manufactured using all non-animal reagents

Storage Class

11 - Combustible Solids

wgk

WGK 1

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Hong-Lin Luo et al.
Cancer cell international, 21(1), 422-422 (2021-08-12)
Epithelial-mesenchymal transition (EMT) promotes migration, invasion, and metastasis of hepatocellular carcinoma (HCC) cells. The molecular mechanisms behind EMT and metastasis in HCC remain unclear. Microarray analysis was used to identify lncRNAs expression during polarization of U937 macrophages from M2 to
Rojo A Ratsimandresy et al.
Nature communications, 8, 15556-15556 (2017-06-06)
Inflammasomes are protein platforms linking recognition of microbe, pathogen-associated and damage-associated molecular patterns by cytosolic sensory proteins to caspase-1 activation. Caspase-1 promotes pyroptotic cell death and the maturation and secretion of interleukin (IL)-1β and IL-18, which trigger inflammatory responses to

Related Content

New Products: Volume 3, 2012

New Products: Antibodies, Assays, Small Molecules, Inhibitors, and Proteins

Global Trade Item Number

SKUGTIN
GF30504053252691461

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service