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Merck

C9008

p-Coumaric acid

≥98% purity (HPLC), powder

Synonym(s):

trans-4-Hydroxycinnamic acid

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About This Item

Linear Formula:
HOC6H4CH=CHCO2H
CAS Number:
501-98-4
Molecular Weight:
164.16
NACRES:
NA.47
PubChem Substance ID:
24893127
UNSPSC Code:
12171500
MDL number:
MFCD00004399
Beilstein/REAXYS Number:
2207383

Product Name

p-Coumaric acid, ≥98.0% (HPLC)

InChI

1S/C9H8O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-6,10H,(H,11,12)/b6-3+

SMILES string

OC(=O)\C=C\c1ccc(O)cc1

InChI key

NGSWKAQJJWESNS-ZZXKWVIFSA-N

assay

≥98.0% (HPLC)

form

powder

technique(s)

titration: suitable

color

white to yellow

mp

214 °C (dec.) (lit.)

solubility

ethanol: 50 mg/mL

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

Quality Level

200

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Application

p-Coumaric acid has been used as a component of chemiluminescent substrate for protein detection in western blotting.

Biochem/physiol Actions

Hydroxycinnamic acid found in many fruits and vegetables.
In western blot, p-coumaric is also used as an enhancer in chemiluminescent substrate.

Other Notes

Predominantly trans isomer.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN3282
BCCM2882
BCCL6658
BCCL0049
BCCJ1325

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Enhanced chemiluminescence (ECL) for routine immunoblotting: An inexpensive alternative to commercially available kits.
Mruk DD and Cheng CY
Spermatogenesis, 1, 121-122 (2011)
Inflammation triggers high mobility group box 1 (HMGB1) secretion in adipose tissue, a potential link to obesity.
Gunasekaran MK, et al.
Cytokine, 64, 103-111 (2013)
A cost effective non-commercial ECL-solution for Western blot detections yielding strong signals and low background.
Haan C and Behrmann I
Journal of Immunological Methods, 318, 11-11 (2007)
TGF-beta receptor levels regulate the specificity of signaling pathway activation and biological effects of TGF-beta.
Rojas A, et al.
Biochimica et Biophysica Acta, 1793, 1165-1173 (2009)
p-Coumaric acid, a common dietary phenol, inhibits platelet activity in vitro and in vivo.
Luceri C, et al.
The British Journal of Nutrition, 97, 458-463 (2007)
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