T0625
Taurine
≥99%
Synonym(s):
2-Aminoethanesulfonic acid
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About This Item
Linear Formula:
NH2CH2CH2SO3H
CAS Number:
Molecular Weight:
125.15
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352106
EC Number:
203-483-8
MDL number:
Beilstein/REAXYS Number:
1751215
Product Name
Taurine, ≥99%
InChI key
XOAAWQZATWQOTB-UHFFFAOYSA-N
InChI
1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6)
SMILES string
NCCS(O)(=O)=O
biological source
synthetic
assay
≥99%
form
powder
color
white
mp
>300 °C (lit.)
application(s)
cell analysis
storage temp.
room temp
Quality Level
Gene Information
human ... GRIN1(2902)
rat ... Ppm1a(24666)
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Application
Taurine has been used for the isolation and growth of taurine-utilizing purple non-sulfur bacteria and in phototrophic growth experiments.
Biochem/physiol Actions
Non-selective endogenous agonist at glycine receptors.
Non-selective endogenous agonist at glycine receptors. Conditionally essential sulfonated amino acid which modulates apoptosis in some cells; functions in many metabolic activities; a product of methionine and cysteine metabolism.
Taurine modulates the concentration of intracellular calcium, protects against ischemia-reperfusion injury and possesses blood pressure-lowering properties. It also has a role in bile formation and fat digestion. Deficiency of taurine is associated with anxiety, hyperactivity, epilepsy and depression.
General description
Taurine (2-aminoethanesulphonic acid) is predominantly found in the retina and heart and is also found in the brain, intestine, skeletal muscles and kidneys.
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Phototrophic utilization of taurine by the purple nonsulfur bacteria Rhodopseudomonas palustris and Rhodobacter sphaeroides.
Novak RT
Microbiology, 150(Pt 6), 1881-1891 (2004)
The potential health benefits of taurine in cardiovascular disease.
Xu YJ
Experimental and Clinical Cardiology, 13(2), 57-65 (2008)
Shozo Sonoda et al.
Nature protocols, 4(5), 662-673 (2009-04-18)
We provide our detailed, standardized in vitro protocol for the culture and differentiation of human retinal pigment epithelial (RPE) cells into a highly polarized and functional monolayer. Disruption of the polarized RPE function plays an important role in the pathogenesis
Felizia K Voss et al.
Science (New York, N.Y.), 344(6184), 634-638 (2014-05-03)
Regulation of cell volume is critical for many cellular and organismal functions, yet the molecular identity of a key player, the volume-regulated anion channel VRAC, has remained unknown. A genome-wide small interfering RNA screen in mammalian cells identified LRRC8A as
Deniz Tasdemir et al.
Bioorganic & medicinal chemistry, 15(21), 6834-6845 (2007-09-04)
The type II fatty acid pathway (FAS-II) is a validated target for antimicrobial drug discovery. An activity-guided isolation procedure based on Plasmodium falciparum enoyl-ACP reductase (PfFabI) enzyme inhibition assay on the n-hexane-, the CHCl(3-) and the aq MeOH extracts of
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