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Merck

227757

Palladium

sulfided, extent of labeling: 5 wt. % loading (dry basis), matrix activated carbon, wet support, (wet)

Synonym(s):

Palladium on carbon, Pd/C

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About This Item

Linear Formula:
Pd
Molecular Weight:
106.42
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
11101718
MDL number:
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Product Name

Palladium, sulfided, extent of labeling: 5 wt. % loading (dry basis), matrix activated carbon, wet support, (wet)

InChI

1S/Pd

SMILES string

[Pd]

InChI key

KDLHZDBZIXYQEI-UHFFFAOYSA-N

form

(wet)

contains

≤50% water

reaction suitability

core: palladium
reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: catalyst

extent of labeling

5 wt. % loading (dry basis)

weight

Unit weight excludes weight of water

matrix

activated carbon, wet support

Quality Level

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Application

Catalyst for:
  • Stille reaction
  • Hydrogenation reactions
  • Suzuki-Miyaura cross-coupling and Heck-Mizoroki reactions
  • Deoxygenation
  • Oxidation reactions
  • Coupling reactions

pictograms

Flame

signalword

Danger

hcodes

Hazard Classifications

Flam. Sol. 1

Storage Class

4.1B - Flammable solid hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Carmen Abate et al.
ChemMedChem, 5(2), 268-273 (2010-01-16)
Sigma-2 (sigma(2)) binding sites are an emerging target for anti-neoplastic agents due to the strong apoptotic effect exhibited by sigma(2) agonists in vitro and the overexpression of these sites in tumor cells. Nonetheless, no sigma(2) receptor protein has been identified.
Carmen Abate et al.
ChemMedChem, 7(10), 1847-1857 (2012-08-15)
σ(2) Receptor research is receiving increasing interest with regard to the potential of σ(2) proteins as targets for tumor therapy and diagnosis. Nevertheless, knowledge about the σ(2) receptor is far from conclusive. The paucity and modest affinity of known σ(2)
Mauro Niso et al.
ChemMedChem, 8(12), 2026-2035 (2013-10-10)
With the aim of contributing to the development of novel antitumor agents, high-affinity σ2 receptor agonists were developed, with 6,7-dimethoxy-2-[4-[1-(4-fluorophenyl)-1H-indol-3-yl]butyl]-1,2,3,4-tetrahydroisoquinoline (15) and 9-[4-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)butyl]-9H-carbazole (25) showing exceptional selectivity for the σ2 subtype. Most of the compounds displayed notable antiproliferative activity in
Carmen Abate et al.
Journal of medicinal chemistry, 57(8), 3314-3323 (2014-04-05)
Despite the promising potentials of σ2 receptors in cancer therapy and diagnosis, there are still ambiguities related to the nature and physiological role of the σ2 protein. With the aim of providing potent and reliable tools to be used in
Carmen Abate et al.
ChemMedChem, 6(1), 73-80 (2010-11-12)
Many new chemotherapeutic agents are under preclinical investigation and, despite efforts to more selectively target cancer cells, limitations such as toxicity and inherent resistance are often encountered. Therefore, alternative strategies are needed to treat cancer and overcome such limitations. We

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