A45807
2-Amino-5-chlorobenzoxazole
97%
Synonym(s):
Zoxazolamine
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About This Item
Empirical Formula (Hill Notation):
C7H5ClN2O
CAS Number:
Molecular Weight:
168.58
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
200-519-4
MDL number:
Assay:
97%
Form:
powder
InChI key
YGCODSQDUUUKIV-UHFFFAOYSA-N
InChI
1S/C7H5ClN2O/c8-4-1-2-6-5(3-4)10-7(9)11-6/h1-3H,(H2,9,10)
SMILES string
Nc1nc2cc(Cl)ccc2o1
assay
97%
form
powder
mp
181-184 °C (lit.)
Quality Level
signalword
Warning
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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K K Anand et al.
Pharmacological research, 36(4), 315-321 (1998-01-13)
Compound I isolated from fraction TB5 of Terminalia belerica and finally identified as 3,4,5-trihydroxy benzoic acid (gallic acid) was evaluated for its hepatoprotective activity against carbon tetrachloride (CCl4)-induced physiological and biochemical alterations in the liver. The main parameters studied were
D J Hadjipavlou-Litina et al.
Research communications in molecular pathology and pharmacology, 96(3), 307-318 (1997-06-01)
Some modified novel thiazol-5yl-aminoketones were evaluated for their anti-inflammatory, analgesic and antiproteolytic activities. Their inhibitory activity on 12-lipoxygenase (12-LO) and beta-glucuronidase in vitro was estimated. Their interaction with the stable free radical 1,1-diphenyl-2-picrylhydrazyl (DPPH) and their RM values were also
Cong Zhang et al.
Nature medicine, 14(9), 959-965 (2008-08-12)
Chaperone-mediated autophagy (CMA), a selective mechanism for degradation of cytosolic proteins in lysosomes, contributes to the removal of altered proteins as part of the cellular quality-control systems. We have previously found that CMA activity declines in aged organisms and have
Huidi Jiang et al.
Die Pharmazie, 58(9), 654-656 (2003-10-09)
The present paper aims to investigate whether p-amino-2',4'-dichlorodiphenyl ether and p-amino-4'-methyldiphenyl ether are inhibitors as well as inducers of P450. Mice were given daily intraperitoneal (ip) injections of p-amino-2',4'-dichlorodiphenyl ether (0.25 mmol/kg) or p-amino-4'-methyldiphenyl ether (0.25 mmol/kg) for 4 days
Juan P Hernandez et al.
Toxicology and applied pharmacology, 216(2), 186-196 (2006-07-11)
Nonylphenol (NP) is a breakdown product of nonylphenol ethoxylates, which are used in a variety of industrial, agricultural, household cleaning, and beauty products. NP is one of the most commonly found toxicants in the United States and Europe and is
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