30461
DEAE-Dextran hydrochloride
BioReagent, Molecular Biology
Synonym(s):
Diethylaminoethyl-dextran hydrochloride
grade
Molecular Biology
product line
BioReagent
form
solid
impurities
DNases, none detected, RNases, none detected, phosphatases, none detected, proteases, none detected
solubility
H2O: 0.1 g/mL, clear
storage temp.
room temp
Quality Level
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Application
DEAE-Dextran, a polycationic stabilizing molecule and transfection reagent, is used in the development of sustained release protein delivery and nucleic acid transfection systems.
Other Notes
To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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S Tabor et al.
Current protocols in immunology, Chapter 10, Unit 10-Unit 10 (2008-04-25)
Extensive knowledge of the enzymology involved in biosynthesis and degradation of nucleic acids has permitted the development of simple methods for labeling RNA and DNA with radioisotopes or biotin. These labeled probes are used primarily for hybridization to nucleic acid
Transfection using DEAE-dextran.
Gulick T.
Current Protocols in Cell Biology, doi: 10-doi: 10 (2003)
Shingo Kikuchi et al.
International journal of pharmaceutics, 386(1-2), 149-155 (2009-11-20)
A multivariate statistical technique was applied to designing a tablet for the sustained release over 24h of diltiazem hydrochloride, a model highly water-soluble drug. Tablets of a hydrophilic matrix composed of dextran derivatives and hypromellose were prepared. The formulations were
Yoshimitsu Doi et al.
Proceedings of the National Academy of Sciences of the United States of America, 105(24), 8381-8386 (2008-06-14)
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) mediated by Th17 and Th1 cells. DNA microarray analysis previously showed that NR4A2, an orphan nuclear receptor, is strongly up-regulated in the peripheral blood T cells of
Laura L Baugh et al.
Journal of virology, 82(19), 9657-9667 (2008-07-26)
The human immunodeficiency virus type 1 (HIV-1) accessory protein Nef downregulates major histocompatibility complex class I (MHC-I) from the cell surface. It has been proposed that the direct interaction of the acidic cluster (AC) of Nef, (62)EEEE(65), with the furin
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