A3882
Alizarin-3-methyliminodiacetic acid
≥98% (TLC), powder
Synonym(s):
N-(carboxymethyl)-N-[(9,10-dihydro-3,4-dihydroxy-9,10-dioxo-2-anthracenyl)methyl]-glycine, 3,4-Dihydroxyanthraquinon-2-yl-methylimino-diacetic acid, Alizarin Complexone, Alizarin Fluorine Blue
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About This Item
Empirical Formula (Hill Notation):
C19H15NO8
CAS Number:
Molecular Weight:
385.32
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
223-544-2
MDL number:
Beilstein/REAXYS Number:
2190028
Product Name
Alizarin-3-methyliminodiacetic acid,
assay
≥98% (TLC)
Quality Level
form
powder
solubility
1 M NaOH: 10 mg/mL, blue to purple
SMILES string
OC(=O)CN(CC(O)=O)Cc1cc2C(=O)c3ccccc3C(=O)c2c(O)c1O
InChI
1S/C19H15NO8/c21-13(22)7-20(8-14(23)24)6-9-5-12-15(19(28)16(9)25)18(27)11-4-2-1-3-10(11)17(12)26/h1-5,25,28H,6-8H2,(H,21,22)(H,23,24)
InChI key
PWIGYBONXWGOQE-UHFFFAOYSA-N
General description
Alizarin-3-methyliminodiacetic acid is used in the colorimetric detection of fluorine. It is a dye employed to stain mineralized bones of the preserved specimen from vertebrates.
Application
Alizarin-3-methyliminodiacetic acid has been used:
- for live staining of mineralized bone matrix
- to double-label the bone for dynamic bone histomorphometry at the femoral mid-diaphysis in the rat
- as a label in histomorphometry of the tibial diaphysis to indicate new bone formation in the rat
Legal Information
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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An evaluation of staining techniques for marking daily growth in scleractinian corals
Holcomb M, et al.
Journal of Experimental Marine Biology and Ecology, 440, 126-131 (2013)
A Bensimon-Brito et al.
BMC developmental biology, 16, 2-2 (2016-01-21)
The correct evaluation of mineralization is fundamental for the study of skeletal development, maintenance, and regeneration. Current methods to visualize mineralized tissue in zebrafish rely on: 1) fixed specimens; 2) radiographic and μCT techniques, that are ultimately limited in resolution;
S Iyama et al.
Journal of periodontology, 68(12), 1169-1175 (1998-01-28)
The present study was designed to compare the amount and regional distribution of bone formation around hydroxyapatite (HA) implants in normal (control) rats with that of animals with diabetes mellitus (DM), induced by streptozotocin 2 weeks prior to implant placement.