C9142
Cyanogen bromide-activated-Sepharose™ 4B
lyophilized powder
Synonym(s):
Cyanogen bromide-activated Agarose
form
lyophilized powder
technique(s)
affinity chromatography: suitable
matrix
Sepharose 4B
matrix active group
cyanate or related structures
matrix spacer
1 atom (when ligands are coupled via isourea derivative or related linkage)
swelling
1 g swells to 4-5 mL
particle size
45—165 μm
storage temp.
2-8°C
Quality Level
Related Categories
General description
Cyanogen bromide-activated-Sepharose™ is suitable for use in affinity chromatography and protein chromatography. It has been used to discover insecticidal agents, raise polyclonal antibodies against yeast invertase glycosyls, and study immunological processes of xenograft rejection.
C9142-15G′s updated product number is GE17-0430-01
C9142-15G′s updated product number is GE17-0430-01
Application
Cyanogen bromide-activated-Sepharose™ 4B has been used:
- in the purification of clusterin from serum by an immunoaffinity-based separation procedure
- in affinity chromatography to isolate Leishmania donovani protein antigens from the urine of visceral leishmaniasis patients
- in affinity chromatography for the isolation of haptoglobin from human serum
Physical form
Lyophilized powder stabilized with lactose and dextran
Legal Information
Sepharose is a trademark of Cytiva
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Kevin K Takaki et al.
Cell host & microbe, 29(1), 58-67 (2020-10-30)
Schistosome eggs provoke the formation of granulomas, organized immune aggregates, around them. For the host, the granulomatous response can be both protective and pathological. Granulomas are also postulated to facilitate egg extrusion through the gut lumen, a necessary step for
Dana A Massuto et al.
Reproduction (Cambridge, England), 139(2), 465-478 (2009-11-19)
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Yan Ling et al.
The Journal of biological chemistry, 282(42), 30804-30816 (2007-08-29)
Farnesyl-diphosphate synthase (FPPS) catalyzes the synthesis of farnesyl diphosphate, an important precursor of sterols, dolichols, ubiquinones, and prenylated proteins. We report the cloning and characterization of two Toxoplasma gondii farnesyl-diphosphate synthase (TgFPPS) homologs. A single genetic locus produces two transcripts
Hans Gaus et al.
Biochemistry, 57(14), 2061-2064 (2018-03-29)
The Stabilin receptors are systemic clearance receptors for some classes of chemically modified nucleic acid therapeutics. In this study, the recombinant human secreted ecto-domain of the small isoform of Stabilin-2 (s190) was purified from cell culture and evaluated for direct
Maia Dorsett et al.
Molecular and cellular biology, 29(22), 6128-6139 (2009-09-16)
During normal development as well as in diseased states such as cancer, extracellular "niches" often provide cues to proximal cells and activate intracellular pathways. Activation of such signaling pathways in turn instructs cellular proliferation and differentiation. In the Caenorhabditis elegans
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