N1514
Nervonic acid
≥99% (capillary GC)
Synonym(s):
cis-15-Tetracosenoic acid, Selacholeic acid
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About This Item
Linear Formula:
CH3(CH2)7CH=CH(CH2)13COOH (cis)
CAS Number:
Molecular Weight:
366.62
UNSPSC Code:
12352211
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1728551
biological source
plant
Quality Level
assay
≥99% (capillary GC)
form
powder
mp
42-43 °C (lit.)
functional group
carboxylic acid
lipid type
unsaturated FAs
shipped in
ambient
storage temp.
−20°C
SMILES string
CCCCCCCC\C=C/CCCCCCCCCCCCCC(O)=O
InChI
1S/C24H46O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24(25)26/h9-10H,2-8,11-23H2,1H3,(H,25,26)/b10-9-
InChI key
GWHCXVQVJPWHRF-KTKRTIGZSA-N
Application
Nervonic acid has been used as a synthetic lipid supplement in vitro to study about effect of the developmental diet in Drosophila lifespan.
Biochem/physiol Actions
Nervonic acid (C24:1), a component of membrane sphingolipids and phosphatidylethanolamines, may be a useful predictor of chronic kidney disease mortality and diabetes. Nervonic acid oils are being studied for pharmaceutical, nutraceutical and industrial applications. Nervonic acid is a major component of Lunaria oil.
Packaging
Sealed ampule.
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Storage Class
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Developmental diet regulates Drosophila lifespan via lipid autotoxins
Stefana MI, et al.
Nature Communications, 8(1), 1384-1384 (2017)
Y Mizushina et al.
Journal of molecular biology, 304(3), 385-395 (2000-11-25)
Unsaturated long-chain fatty acids selectively bind to the DNA binding sites of DNA polymerase beta and DNA topoisomerase II, and inhibit their activities, although the amino acid sequences of these enzymes are markedly different from each other. Computer modeling analysis
Arja T Erkkilä et al.
The Journal of craniofacial surgery, 16(5), 764-769 (2005-09-30)
The fatty acid profiles of serum lipids were examined in 53 ten-year-old cleft children. The children presented with different cleft types (cleft lip, cleft lip and palate, isolated cleft palate and submucuous cleft palate) and were recruited from the Finnish