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392995

Coumarin 314

Dye content 97 %

Synonym(s):

2,3,5,6-1H,4H-Tetrahydro-9-carbethoxyquinolizino-[9,9a,1-gh]coumarin, Coumarin 504

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About This Item

Empirical Formula (Hill Notation):
C18H19NO4
CAS Number:
55804-66-5
Molecular Weight:
313.35
NACRES:
NA.47
PubChem Substance ID:
24864155
UNSPSC Code:
12171500
EC Number:
259-825-1
MDL number:
MFCD00051334
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form

solid

Quality Level

200

composition

Dye content, 97%

mp

140-144 °C (lit.), 146.22-147.36 °C (lit.)

λmax

436 nm, 437 nm in ethanol

ε (extinction coefficient)

≥39000 at 389-401 nm in ethanol at 0.01 g/L

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

CCOC(=O)C1=Cc2cc3CCCN4CCCc(c2OC1=O)c34

InChI

1S/C18H19NO4/c1-2-22-17(20)14-10-12-9-11-5-3-7-19-8-4-6-13(15(11)19)16(12)23-18(14)21/h9-10H,2-8H2,1H3

InChI key

VMJKUPWQKZFFCX-UHFFFAOYSA-N

Application

Laser dye.
Suitable as a laser dye

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
MKCL0209
MKCK9667
MKCK9666
MKBH4061V
07913DH

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Seok Chan Park et al.
Polymers, 11(2) (2019-04-10)
In this study we present polymeric microneedles composed of multiple layers to control drug release kinetics. Layered microneedles were fabricated by spraying poly(lactic-co-glycolic acid) (PLGA) and polyvinylpyrrolidone (PVP) in sequence, and were characterized by mechanical testing and ex vivo skin
Jason V Gregory et al.
Advanced healthcare materials, 9(21), e2000564-e2000564 (2020-09-23)
Delivery of multiple therapeutics has become a preferred method of treating cancer, albeit differences in the biodistribution and pharmacokinetic profiles of individual drugs pose challenges in effectively delivering synergistic drug combinations to and at the tumor site. Here, bicompartmental Janus
Andrea Doni et al.
The Journal of experimental medicine, 212(6), 905-925 (2015-05-13)
Pentraxin 3 (PTX3) is a fluid-phase pattern recognition molecule and a key component of the humoral arm of innate immunity. In four different models of tissue damage in mice, PTX3 deficiency was associated with increased fibrin deposition and persistence, and