54965
(±)-Sodium 3-hydroxybutyrate
≥99.0% (NT)
Synonym(s):
(±)-3-Hydroxybutyric acid sodium salt
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About This Item
Linear Formula:
CH3CH(OH)CH2COONa
CAS Number:
Molecular Weight:
126.09
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
205-774-5
Beilstein/REAXYS Number:
4824866
MDL number:
Product Name
(±)-Sodium 3-hydroxybutyrate, ≥99.0% (NT)
InChI key
NBPUSGBJDWCHKC-UHFFFAOYSA-M
InChI
1S/C4H8O3.Na/c1-3(5)2-4(6)7;/h3,5H,2H2,1H3,(H,6,7);/q;+1/p-1
SMILES string
[Na+].CC(O)CC([O-])=O
assay
≥99.0% (NT)
mp
167-170 °C
functional group
hydroxyl
Quality Level
Related Categories
Application
(±)-Sodium 3-hydroxybutyrate has been used in a study to understand the effect of butyrate on fibroblast growth factor 21 (FGF21), which is involved in fatty acid ß-oxidation in liver. It may be used in the preparation of poly(3-hydroxybutyrate).
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Shengying Pan et al.
Behavioural pharmacology, 31(4), 322-332 (2020-01-03)
β-hydroxybutyrate, a ketone body metabolite, has been shown to suppress depression-like behavior in rodents. In this study, we examined its antidepressive property in acute and chronic administration modes in mice by using forced swim test and tail suspension test. Results
Roman Tyzio et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 31(1), 34-45 (2011-01-07)
GABA depolarizes immature neurons because of a high [Cl(-)](i) and orchestrates giant depolarizing potential (GDP) generation. Zilberter and coworkers (Rheims et al., 2009; Holmgren et al., 2010) showed recently that the ketone body metabolite DL-3-hydroxybutyrate (DL-BHB) (4 mM), lactate (4
Sodium butyrate stimulates expression of fibroblast growth factor 21 in liver by inhibition of histone deacetylase 3.
Li H, et al.
Diabetes, 61(4), 797-806 (2012)
Novel synthesis of poly (3-hydroxybutyrate).
Juzwa M and Jedli?ski Z.
Macromolecules, 39(13), 4627-4630 (2006)
Nikolaj Rittig et al.
Shock (Augusta, Ga.), 44(1), 32-35 (2015-04-22)
Endotoxin administrations are used in experimental models of inflammatory disease. Short-term endotoxin tolerance in response to repeated endotoxin exposure is well known, but the duration of endotoxin tolerance in humans remains unknown. The main purpose of this study was to
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