Skip to Content
Merck

Key Documents

View All Documentation

8.51061

2-Chlorotrityl chloride

Novabiochem®

Synonym(s):

2-Chlorotrityl chloride

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C19H14Cl2
CAS Number:
42074-68-0
Molecular Weight:
313.22
UNSPSC Code:
12352107
EC Index Number:
255-647-3
NACRES:
NA.22
MDL number:
MFCD00040399
Assay:
≥95.0% (HPLC)
Form:
powder
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Quality Level

200

product line

Novabiochem®

assay

≥95.0% (HPLC)

form

powder

manufacturer/tradename

Novabiochem®

mp

133.0-137.0 °C

application(s)

peptide synthesis

storage temp.

2-30°C

SMILES string

ClC(c3c(cccc3)Cl)(c2ccccc2)c1ccccc1

InChI

1S/C19H14Cl2/c20-18-14-8-7-13-17(18)19(21,15-9-3-1-4-10-15)16-11-5-2-6-12-16/h1-14H

InChI key

JFLSOKIMYBSASW-UHFFFAOYSA-N

General description

Hyperacid-labile ester protecting group [1]. Introduced under extremely mild conditions by reacting together the acid, trityl chloride and DIPEA in DCM. Ideal for the protection of the C-terminal carboxylic acid group of C-terminal protected peptide fragments, monoprotection of diacids and as a general carboxylic acid protecting group in organic synthesis.


Associated Protocols and Technical Articles
Guide to Selection of Orthogonally-Protected Building Blocks for Fmoc SPPS

Literature references

[1] P. Athanassopoulos, et al. (1995) Tetrahedron Lett., 36, 5645.

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Melting range (lower value): ≥ 133 °C
Melting range (upper value): ≤ 137 °C
Assay (HPLC, area%): ≥ 95.0 % (a/a)

Other Notes

Replaces: 01-63-0045

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Still not finding the right product?

Explore all of our products under 2-Chlorotrityl chloride

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

8A - Combustible, corrosive hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library