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Merck

8.52100

Fmoc-Lys(biotinyl-ε-aminocaproyl)-OH

Novabiochem®

Synonym(s):

Fmoc-Lys(biotinyl-ε-aminocaproyl)-OH, N-α-Fmoc-N-ε-(biotinylcaproyl)-L-lysine

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About This Item

Empirical Formula (Hill Notation):
C37H49N5O7S
CAS Number:
Molecular Weight:
707.88
MDL number:
UNSPSC Code:
12352209
NACRES:
NA.22
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Quality Level

product line

Novabiochem®

assay

≥90.0% (HPLC), ≥98% (TLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

biotin

storage temp.

2-30°C

SMILES string

S1[C@H]([C@H]5NC(=O)N[C@H]5C1)CCCCC(=O)NCCCCCC(=O)NCCCC[C@H](NC(=O)OCC2c3c(cccc3)c4c2cccc4)C(=O)O

InChI

1S/C37H49N5O7S/c43-32(18-2-1-10-20-38-33(44)19-8-7-17-31-34-30(23-50-31)40-36(47)42-34)39-21-11-9-16-29(35(45)46)41-37(48)49-22-28-26-14-5-3-12-24(26)25-13-4-6-15-27(25)28/h3-6,12-15,28-31,34H,1-2,7-11,16-23H2,(H,38,44)(H,39,43)(H,41,48)(H,45,46)(H2,40,42

InChI key

SLWMKSMUFPMDKA-MEROQGEASA-N

General description

A modified lysine derivative for the preparation of biotin-labeled peptides by Fmoc SPPS, in which the biotin is separated from the lysine side-chain by a 6 C-atom spacer.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Biotinylation Reagents for Peptide Synthesis

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in DMF): +11.5 - +16.0 °
Purity (TLC(CMA2)): ≥ 98 %
Assay (HPLC, area%): ≥ 90.0 % (a/a)
Solubility (100mg in 10 ml DMF): clearly soluble
This product can obtain up to 10% DMF in order to assure an ideal solubility.

To see the solvent systems used for TLC of Novabiochem® products please click here.

Other Notes

Replaces: 04-12-1243

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany


Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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