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Merck

10812846001

Roche

Tris hydrochloride

>99% (titration), pH 7.0-9.0, suitable for FISH

Synonym(s):

Trizma® hydrochloride, TRIS HCl, TRIS hydrochloride, Tris(hydroxymethyl)aminomethane hydrochloride, Tromethane hydrochloride

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About This Item

Linear Formula:
NH2C(CH2OH)3 · HCl
CAS Number:
Molecular Weight:
157.60
PubChem Substance ID:
UNSPSC Code:
12161700
Beilstein/REAXYS Number:
3675235
MDL number:
NACRES:
NA.54
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assay

>99% (titration)

form

solid

packaging

pkg of 500 g

manufacturer/tradename

Roche

technique(s)

FISH: suitable

pH

7.0-9.0

useful pH range

7.0-9.0

pKa (25 °C)

8.1

absorption

<0.02 at 300 nm at 100 mg/mL

storage temp.

room temp

SMILES string

Cl.NC(CO)(CO)CO

InChI

1S/C4H11NO3.ClH/c5-4(1-6,2-7)3-8;/h6-8H,1-3,5H2;1H

InChI key

QKNYBSVHEMOAJP-UHFFFAOYSA-N

Application

Buffering agent in incubation mixtures. It has also been used as a component of lysis and TE (Tris-EDTA) buffer.

Features and Benefits

Crystals

Analysis Note

Purity: >99% Tris-HCl (titrimetric)
Heavy metals: <1 ppm Pb and Fe

Other Notes

The pH values of all buffers are temperature and concentration dependent. For Tris buffers, pH increases about 0.03 unit per °C decrease in temperature, and decreases 0.03-0.05 unit per ten-fold dilution. For precise applications, use a carefully calibrated pH meter with a glass/calomel combination electrode.

Legal Information

Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany


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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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