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296309

1,4-Dioxane

anhydrous, 99.8%, contains <=50 ppm BHT as stabilizer

Synonym(s):

Diethylene oxide, Dioxane

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About This Item

Linear Formula:
C4H8O2
CAS Number:
123-91-1
Molecular Weight:
88.11
UNSPSC Code:
12352005
NACRES:
NA.21
PubChem Substance ID:
57648388
EC Number:
204-661-8
Beilstein/REAXYS Number:
102551
MDL number:
MFCD00006571
Assay:
99.8%
Grade:
anhydrous
Bp:
100-102 °C (lit.)
Vapor pressure:
27 mmHg ( 20 °C), 40 mmHg ( 25 °C)
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grade

anhydrous

Quality Segment

200

vapor density

3 (vs air)

vapor pressure

27 mmHg ( 20 °C), 40 mmHg ( 25 °C)

assay

99.8%

form

liquid

autoignition temp.

356 °F

expl. lim.

22 %

impurities

<0.003% water, <0.005% water (100 mL pkg)

evapn. residue

≤0.005%

refractive index

n20/D 1.422 (lit.)

pH

6.0-8 (20 °C, 500 g/L)

bp

100-102 °C (lit.)

mp

10-12 °C (lit.)

density

1.034 g/mL at 25 °C (lit.)

SMILES string

C1COCCO1

InChI

1S/C4H8O2/c1-2-6-4-3-5-1/h1-4H2

InChI key

RYHBNJHYFVUHQT-UHFFFAOYSA-N

General description

Our anhydrous solvents deliver exceptionally low water content, making them the ideal choice for moisture-sensitive laboratory applications. Packaged in the exclusive Sure/Seal™ septum bottle system, they are reliably protected against moisture ingress from first use to last drop. The innovative Sure/Seal™ closure combines an advanced plug-style liner with an airtight elastomer and crimp cap design to ensure consistent product integrity. Three unique liner materials provide optimal chemical compatibility across a broad range of solvents. Sure/Seal™ packaging is proven to maintain anhydrous conditions even after repeated punctures. With more than 70 products across all major solvent families, available in pack sizes from 100 mL to 2 L, the portfolio meets virtually every laboratory need. By choosing ready-to-use anhydrous solvents in Sure/Seal™ packaging, researchers eliminate the need for time-consuming and hazardous in-house solvent drying and distillation - saving time, reducing risk, and improving reproducibility.

Application

Anhydrous solvents in Sure/Seal™ packaging are essential wherever water contamination would compromise experimental results. They are widely used in moisture-sensitive applications such as organic synthesis - including Grignard reactions, organometallic chemistry, and catalysis - as well as in peptide, oligonucleotide, and pharmaceutical synthesis.

Packaging

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Other Notes

The article number 296309-4X2L will be discontinued. Please order the single bottle 296309-2L which is physically identical with the same exact specifications.

Legal Information

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

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Danger

Hazard Classifications

Carc. 1B - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

target_organs

Respiratory system

supp_hazards

EUH019,EUH066

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

51.8 °F - closed cup

flash_point_c

11 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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