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Merck

317802

4-(4-Isothiocyanatophenylazo)-N,N-dimethylaniline

97%

Synonym(s):

4-(Dimethylamino)azobenzene-4′-isothiocyanate, DABITC

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About This Item

Linear Formula:
SCNC6H4N=NC6H4N(CH3)2
CAS Number:
7612-98-8
Molecular Weight:
282.36
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
24859100
EC Number:
231-521-3
Beilstein/REAXYS Number:
752568
MDL number:
MFCD00004812

Key Documents

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InChI key

OSWZKAVBSQAVFI-ISLYRVAYSA-N

InChI

1S/C15H14N4S/c1-19(2)15-9-7-14(8-10-15)18-17-13-5-3-12(4-6-13)16-11-20/h3-10H,1-2H3/b18-17+

SMILES string

CN(C)c1ccc(cc1)\N=N\c2ccc(cc2)N=C=S

assay

97%

form

crystals

mp

167-171 °C (lit.)

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

Related Categories

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H317,H334

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKBC7832
14127JI
12029JC
09630CC
06912HO

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I Jelesarov et al.
European journal of biochemistry, 216(1), 57-66 (1993-08-15)
The chloroplast enzyme ferredoxin: NADP+ reductase (FNR) catalyzes the reduction of NADP+ by ferredoxin (Fd). FNR and Fd form a 1:1 complex that is stabilized by electrostatic interactions between acidic residues of Fd and basic residues of FNR. To localize
A Wawrzynów et al.
Biochimica et biophysica acta, 1203(1), 60-70 (1993-11-10)
The Ca(2+)-ATPase protein of rabbit skeletal muscle sarcoplasmic reticulum is a single polypeptide chain of 1001 amino-acid residues. Among these residues are 24 Cys, 9 of which have previously been shown to be accessible to one or more thiol-specific reagents.
J Y Chang et al.
Biochemistry, 31(11), 2874-2878 (1992-03-24)
Recombinant human interleukin-1 beta (h-IL-1 beta) was chemically modified with 4-(N,N-dimethylamino)-4'-isothiocyanatoazobenzene-2'-sulfonic acid (S-DABITC), a water-soluble color reagent specific for lysine labeling. Modified h-IL-1 beta was digested by lysyl endopeptidase. Peptides containing labeled lysines were detected at the visible wavelength (436
P Mellet et al.
Biochemistry, 34(8), 2645-2652 (1995-02-28)
Heparin accelerates the inhibition of neutrophil elastase by mucus proteinase inhibitor (MPI), the physiological antielastase of airways as a result of its binding with the inhibitor [Faller, B., Mély, Y., Gérard, D., & Bieth, J. G. (1992) Biochemistry 31, 8285-8290].
[DABITC microsequence analysis of proteins].
H Hirano
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 29(5), 374-382 (1984-05-01)
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