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Merck

P3657

Pyridoxal 5′-phosphate hydrate

powder, BioReagent, suitable for cell culture

Synonym(s):

3-Hydroxy-2-methyl-5-([phosphonooxy]methyl)-4-pyridinecarboxaldehyde, Codecarboxylase, PLP, Pyridoxal 5-phosphate

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About This Item

Empirical Formula (Hill Notation):
C8H10NO6P · xH2O
CAS Number:
Molecular Weight:
247.14 (anhydrous basis)
UNSPSC Code:
12352205
NACRES:
NA.75
PubChem Substance ID:
EC Number:
200-208-3
Beilstein/REAXYS Number:
234749
MDL number:
Technical Service
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product line

BioReagent

Quality Segment

assay

≥98%

form

powder

mol wt

Mw 247.14 g/mol

technique(s)

cell culture | mammalian: suitable

color

off-white to yellow-brown

mp

140-143 °C

solubility

1 M HCl: soluble 50 mg/mL, clear, colorless to light yellow-green

storage temp.

−20°C

SMILES string

CC1=NC=C(COP(O)(O)=O)C(C([H])=O)=C1O

InChI

1S/C8H10NO6P/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14/h2-3,11H,4H2,1H3,(H2,12,13,14)

InChI key

NGVDGCNFYWLIFO-UHFFFAOYSA-N

General description

Pyridoxal-phosphate (PLP, pyridoxal-5′-phosphate, P5P) is a prosthetic group of some enzymes. It is the active form of vitamin B6, which comprises three natural organic compounds, pyridoxal, pyridoxamine and pyridoxine. PLP acts as a coenzyme in all transamination reactions, and in some decarboxylation and deamination reactions of amino acids.

Application


  • Hierarchical Surface Architecture of Hemodialysis Membranes for Eliminating Homocysteine Based on the Multifunctional Role of Pyridoxal 5′-phosphate.: Discusses the development of advanced hemodialysis membranes using pyridoxal 5′-phosphate, highlighting its role in reducing homocysteine levels, which could contribute to improved outcomes for dialysis patients (Jiang P et al., 2020).



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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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