218745
Caspase Inhibitor III
The Caspase Inhibitor III, also referenced under CAS 634911-80-1, controls the biological activity of Caspase. This small molecule/inhibitor is primarily used for Cancer applications.
Synonym(s):
Caspase Inhibitor III, Boc-D-FMK
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About This Item
Empirical Formula (Hill Notation):
C11H18FNO5
CAS Number:
Molecular Weight:
263.26
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77
Quality Level
form
semisolid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated
color
off-white
solubility
DMSO: 5 mg/mL
shipped in
ambient
storage temp.
−20°C
SMILES string
FCC(=O)C(NC(=O)OC(C)(C)C)CC(=O)OC
InChI
1S/C11H18FNO5/c1-11(2,3)18-10(16)13-7(8(14)6-12)5-9(15)17-4/h7H,5-6H2,1-4H3,(H,13,16)
InChI key
MXOOUCRHWJYCAL-UHFFFAOYSA-N
General description
A broad-spectrum cell-permeable and irreversible caspase inhibitor.
A cell-permeable, irreversible, broad-spectrum caspase inhibitor.
Biochem/physiol Actions
Cell permeable: yes
Primary Target
broad spectrum caspase
broad spectrum caspase
Product does not compete with ATP.
Reversible: no
Preparation Note
Following reconstitution aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for up to 4 months at 4°C or for up to 1 year at -20°C.
Analysis Note
single spot by TLC
Other Notes
Boc-Asp(OMe)-CH₂F*
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
D’Mello, S.R., et al. 1998. J. Neurochem. 70, 1809.
D’Mello, S.R., et al. 1998. J. Neurochem. 70, 1809.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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