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73658

Ginsenoside Rh2

analytical standard

Synonym(s):

(3β,12β)-12,20-Dihydroxydammar-24-en-3-yl-β-D-glucopyranoside, 20(S)-Ginsenoside-Rh2

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About This Item

Empirical Formula (Hill Notation):
C36H62O8
CAS Number:
78214-33-2
Molecular Weight:
622.87
NACRES:
NA.24
PubChem Substance ID:
329765120
UNSPSC Code:
85151701
MDL number:
MFCD00800712
Technical Service
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grade

analytical standard

Quality Level

100

assay

≥97.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

C\C(C)=C/CC[C@](C)(O)[C@H]1CC[C@]2(C)[C@@H]1[C@H](O)C[C@@H]3[C@@]4(C)CC[C@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)C(C)(C)[C@@H]4CC[C@@]23C

InChI

1S/C36H62O8/c1-20(2)10-9-14-36(8,42)21-11-16-35(7)27(21)22(38)18-25-33(5)15-13-26(32(3,4)24(33)12-17-34(25,35)6)44-31-30(41)29(40)28(39)23(19-37)43-31/h10,21-31,37-42H,9,11-19H2,1-8H3/t21-,22+,23+,24-,25+,26-,27-,28+,29-,30+,31-,33-,34+,35+,36-/m0/s1

InChI key

CKUVNOCSBYYHIS-IRFFNABBSA-N

General description

Ginsenoside Rh2 is an active component of Red P. ginseng. It is reported to be obtained as a metabolite of ginsenoside Rg3, when anaerobically incubated with human fecal microflora.

Application

Ginsenoside Rh2 may be used as an analytical reference standard for the quantification of the analyte in plasma samples using high-performance liquid chromatography technique.[24]
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

This compound is commonly found in plants of the genus: panax

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pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN7115
BCCM5602
BCCH1115
BCCG0514
BCBV9500

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Long He et al.
Bone, 50(6), 1207-1213 (2012-04-10)
Ginsenoside Rh2 is one of the most active components of red ginseng, controlling cancer and other metabolic diseases including osteoclast differentiation. However, the molecular mechanism underlying the inhibition of osteoclast differentiation by ginsenoside Rh2 remains poorly understood. In the present
Liang Li et al.
Drug metabolism and disposition: the biological fate of chemicals, 40(10), 2041-2053 (2012-07-26)
20(S)-Ginsenoside Rh2 (Rh2)-containing products are widely used in Asia, Europe, and North America. However, extremely limited metabolism information greatly impedes the complete understanding of its clinical safety and effectiveness. The present study aims to systematically investigate the oxidative metabolism of
Y Wang et al.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 44(1), 33-40 (2011-12-30)
The present study was designed to determine the antihyperglycemic function of ginsenoside Rh2 (GS-Rh2) by the regeneration of β-cells in mice that underwent 70% partial pancreatectomy (PPx), and to explore the mechanisms of GS-Rh2-induced β-cell proliferation. Adult C57BL/6J mice were
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