14050
Berberine chloride hydrate
technical, ≥90% (AT)
Synonym(s):
Natural Yellow 18
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About This Item
Empirical Formula (Hill Notation):
C20H18ClNO4 · xH2O
CAS Number:
Molecular Weight:
371.81 (anhydrous basis)
UNSPSC Code:
12352103
NACRES:
NA.22
PubChem Substance ID:
EC Number:
211-195-9
Colour Index Number:
75160
MDL number:
Product Name
Berberine chloride hydrate, technical, ≥90% (AT)
InChI key
VKJGBAJNNALVAV-UHFFFAOYSA-M
InChI
1S/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;/p-1
SMILES string
[Cl-].COc1ccc2cc3-c4cc5OCOc5cc4CC[n+]3cc2c1OC
grade
technical
assay
≥90% (AT)
form
powder
mp
204-206 °C (dec.)
Quality Level
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Lamyae El Khalki et al.
Molecules (Basel, Switzerland), 25(3) (2020-01-30)
Triple negative breast cancer (TNBC) is an aggressive breast cancer subtype. Non-available targeted therapy for TNBC represents its biggest treatment challenge. Thus, finding new promising effective drugs is urgently needed. In the present study, we investigated how berberine, a natural
Optimized piperine-phospholipid complex with enhanced bioavailability and hepatoprotective activity.
Sayan Biswas et al.
Pharmaceutical development and technology, 26(1), 69-80 (2020-10-17)
Piper species is one of the most widely consumed spices for culinary purposes. Piperine (PIP) present in Piper species has a wide range of therapeutic activity including hepatoprotection. However, the major biological limitation of PIP is its low bioavailability after
Li Jia et al.
Mediators of inflammation, 2020, 9419085-9419085 (2020-10-17)
Berberine (BER), a natural isoquinoline alkaloid, has been demonstrated to have appreciable anticolitis effects. Nevertheless, the protective mechanism of BER in ulcerative colitis (UC) is barely understood. The present study was aimed at exploring the therapeutic efficacy of BER on
Cemile Selin Aksoy et al.
Microbial pathogenesis, 149, 104542-104542 (2020-10-04)
A plethora of natural products emerges as attractive molecules in the struggle against antibiotic resistance. These molecules impose their bioactivities not only alone but also in combinations as well, which further enhances their effects. Berberine is a well-known isoquinoline alkaloid
Effects of berberine on amelioration of hyperglycemia and oxidative stress in high glucose and high fat diet-induced diabetic hamsters in vivo.
Liu C, Wang Z, Song Y, et al.
BioMed Research International, 2015, 313808-313808 (2015)
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