202444
Poly(ethylene glycol)
average MN 3,350, hydroxyl, powder
Synonym(s):
Polyethylene glycol, PEG
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About This Item
Linear Formula:
H(OCH2CH2)nOH
CAS Number:
UNSPSC Code:
12352104
PubChem Substance ID:
NACRES:
NA.23
MDL number:
Product Name
Poly(ethylene glycol), average Mn 3,350, powder
SMILES string
C(CO)O
InChI
1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI key
LYCAIKOWRPUZTN-UHFFFAOYSA-N
form
powder
mol wt
average Mn 3,350
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pH
4.5-7.5
viscosity
90 cSt(210 °F) (99 °C)(lit.)
mp
54-58 °C (lit.)
density
1.204 g/mL at 25 °C
Ω-end
hydroxyl
α-end
hydroxyl
greener alternative category
Quality Level
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Application
PEG can be used to functionalize magnetite nanoparticles. The coating of the magnetic core with PEG provides good stabilization while maintaining the magnetic properties of the nanoparticles.
It can be used to modify the surface of photocatalytic TiO2 nanopowder for its application in self-cleaning paints. PEG-coated TiO2 nanopowder can be prepared under mild conditions and show excellent colloidal stability.
It can be used as a cross-linker to prepare poly(N-isopropylacrylamide) based thermosensitive injectable hydrogels. The addition of PEG improves the chemical and mechanical properties of hydrogel and prevents it from dissolving in the swelling medium. Owing to their biocompatibility and biodegradability, these hydrogels are widely used for biomedical applications.
It can be used to modify the surface of photocatalytic TiO2 nanopowder for its application in self-cleaning paints. PEG-coated TiO2 nanopowder can be prepared under mild conditions and show excellent colloidal stability.
It can be used as a cross-linker to prepare poly(N-isopropylacrylamide) based thermosensitive injectable hydrogels. The addition of PEG improves the chemical and mechanical properties of hydrogel and prevents it from dissolving in the swelling medium. Owing to their biocompatibility and biodegradability, these hydrogels are widely used for biomedical applications.
Features and Benefits
- High structural flexibility
- Biocompatibility
- High hydration capacity
- Devoid of any steric hindrance
General description
Poly(ethylene glycol) (PEG) is a biocompatible inert synthetic polymer with repeating units of ether oxygen (-CH2-CH2-O-). It can be synthesized via anionic polymerization of ethylene oxide. It is extensively used in biological and medical applications due to its non-immunogenicity and high water solubility.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.
Other Notes
Molecular weight: Mn 3,015-3,685
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Grant A Robinson et al.
Journal of neuroscience research, 94(7), 636-644 (2016-03-21)
Functional recovery following a peripheral nerve injury is made easier when regenerating axons correctly reinnervate their original targets. Polyethylene glycol (PEG) has recently been used in attempts to fuse severed peripheral axons during suture-based repair, but an analysis of target
Erinna F Lee et al.
Autophagy, 15(5), 785-795 (2019-01-11)
BECN1/Beclin 1 is a critical protein in the initiation of autophagosome formation. Recent studies have shown that phosphorylation of BECN1 by STK4/MST1 at threonine 108 (T108) within its BH3 domain blocks macroautophagy/autophagy by increasing BECN1 affinity for its negative regulators
Yixu Wang et al.
mSphere, 4(3) (2019-05-31)
Sporisorium scitamineum is the fungal pathogen causing severe sugarcane smut disease that leads to massive economic losses globally. S. scitamineum invades host cane by dikaryotic hyphae, formed after sexual mating of two haploid sporidia of opposite mating type. Therefore, mating/filamentation
Idalis Villanueva et al.
Acta biomaterialia, 5(8), 2832-2846 (2009-06-11)
The pericellular matrix (PCM) surrounding chondrocytes is thought to play an important role in transmitting biochemical and biomechanical signals to the cells, which regulates many cellular functions including tissue homeostasis. To better understand chondrocytes interactions with their PCM, three-dimensional poly(ethylene
Mark A Rice et al.
Acta biomaterialia, 5(1), 152-161 (2008-09-17)
Ultrasound has potential as a non-destructive analytical technique to provide real-time online assessments of matrix evolution in cell-hydrogel constructs used in tissue engineering. In these studies, chondrocytes were encapsulated in poly(ethylene glycol) hydrogels, and gel degradation was manipulated to provide
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