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About This Item
Linear Formula:
CH3(OCH2CH2)nOH
CAS Number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23
MDL number:
Product Name
Poly(ethylene glycol) methyl ether, average Mn 750
vapor density
>1 (vs air)
Quality Level
vapor pressure
0.05 mmHg ( 20 °C)
form
paste, solid
mol wt
average Mn 750
refractive index
n20/D 1.459
viscosity
10.5 cSt(210 °F)(lit.)
transition temp
Tm 30 °C
density
1.094 g/mL at 25 °C
Ω-end
hydroxyl
α-end
methoxy
SMILES string
O(CCO)C
InChI
1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3
InChI key
XNWFRZJHXBZDAG-UHFFFAOYSA-N
Application
Poly(ethylene glycol) methyl ether can be used:
- As a chain transfer agent to synthesize amphiphilic block copolymers by metal-free ring-opening oligomerization.
- As a precursor to prepare retinoic acid-polyethylene glycol nanoassembly as an efficient drug delivery system.
- To prepare diblock copolymer with polylactic acid, which can be applied in the field of tissue engineering and drug delivery.
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Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
359.6 °F - closed cup
flash_point_c
182 °C - closed cup
ppe
Eyeshields, Gloves
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Yi Wei et al.
Langmuir : the ACS journal of surfaces and colloids, 28(39), 13984-13992 (2012-09-04)
The microcosmic mechanisms of protein (recombinant human growth hormone, rhGH) incomplete release and stability from amphiphilic poly(monomethoxypolyethylene glycol-co-D,L-lactide) (mPEG-PLA, PELA) microspheres were investigated. PELA with different hydrophilicities (PELA-1, PELA-2, and PELA-3) based on various ratios of mPEG to PLA were
Curcumin loaded polymeric micelles inhibit breast tumor growth and spontaneous pulmonary metastasis.
Lei Liu et al.
International journal of pharmaceutics, 443(1-2), 175-182 (2013-01-05)
This work aims to develop curcumin (Cur) loaded biodegradable self-assembled polymeric micelles (Cur-M) to overcome poor water solubility of Cur and to meet the requirement of intravenous administration. Cur-M were prepared by solid dispersion method, which was simple and easy
Yiyi Yu et al.
Journal of pharmaceutical sciences, 102(3), 1054-1062 (2013-01-03)
To promote the application of methoxy poly(ethylene glycol)-cholesterol (mPEG-Chol), mPEG-Chol was used to prepare core-shell micelles encapsulating poorly water-soluble docetaxel (DTX-PM) by modified cosolvent evaporation method. Approaches to enhance DTX entrapment efficiency (EE) and minimize particle size were investigated in