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Merck

388246

Dimethylamine solution

2.0 M in methanol

Synonym(s):

N,N-Dimethylamine

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About This Item

Linear Formula:
(CH3)2NH
CAS Number:
124-40-3
Molecular Weight:
45.08
UNSPSC Code:
12352116
NACRES:
NA.22
PubChem Substance ID:
24864215
MDL number:
MFCD00008288
Beilstein/REAXYS Number:
605257

Product Name

Dimethylamine solution, 2.0 M in methanol

InChI

1S/C2H7N/c1-3-2/h3H,1-2H3

SMILES string

CNC

InChI key

ROSDSFDQCJNGOL-UHFFFAOYSA-N

form

liquid

concentration

1.90 -2.20 M (NaOH, titration)
2.0 M in methanol

density

0.775 g/mL at 25 °C

functional group

amine

Quality Level

200

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Application

Dimethylamine can be used as a precursor for the preparation of a number of chemical building blocks such as dimethyl(3-chloropropyl)amine , 2-chloro-N,N-dimethylethanimidamide , and 4, 6-dichloro-2-(dimethylamino)-1,3,5-triazine .

General description

Dimethylamine, a secondary amine, is used as a raw material for the production of many agrichemicals and pharmaceuticals. The solvents dimethylformamide (DMF) and dimethylacetamide (DMA) are derived from dimethylamine. It is also used as a precursor for the preparation of amido derivatives.

Packaging

The 25 mL Sure/Seal™ bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product.

Legal Information

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

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Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 1 - STOT SE 3

target_organs

Eyes, Respiratory system

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

41.0 °F - closed cup

flash_point_c

5 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Certificates of Analysis (COA)

Lot/Batch Number
SHBN5212
SHBN5211
SHBN4661
SHBN3189
SHBL9825

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4-Dimethylaminobutyraldehyde diethyl acetal
FENG R-l, et al.
JOURNAL-SHANDONG UNIVERSITY OF SCIENCE AND TECHNOLOGY NATURAL SCIENCE, 5 (2011)
Synthesis of 2-amino-4-imino-4, 5-dihydrothiazoles from N-sulfonyl-α -chloroamidines and thiourea
Abdelaal SM and Bauer L
Journal of Heterocyclic Chemistry, 25(6), 1849-1856 (1988)
Synthesis of 3-{4-[4-dimethylamino-6-(4-methyl-2-oxo-2H-chromen-7-yloxy)-[1, 3, 5] triazin-2-ylamino]-phenyl}-2-phenyl-5-(4-pyridin-2-yl-piperazin-1-ylmethyl)-thiazolidin-4-one and their biological evaluation
Patel D, et al.
Medicinal Chemistry Research, 21(10), 2926-2944 (2012)
Methylamines
van Gysel A B and Musin W
Ullmann's Encyclopedia of Industrial Chemistry (1997)
C Mulder et al.
Journal of neural transmission (Vienna, Austria : 1996), 109(9), 1203-1208 (2002-08-31)
Nitric oxide (NO) may play a role in the pathophysiology of Alzheimer's disease (AD). Asymmetric dimethylarginine (ADMA), an endogenous inhibitor of NO synthase, is involved in regulation of NO production. Recently it has been reported that dimethylarginine dimethylaminohydrolase, an enzyme
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